Evidence map›Paper›PMID 29868034›Full record

ArticleFrontiers in immunology2018

The CXC Chemokine Receptor 3 Inhibits Autoimmune Cholangitis

Qing-Zhi Liu, Wen-Tao Ma, Jing-Bo Yang, Zhi-Bin Zhao, Kai Yan, Yuan Yao, Liang Li, Qi Miao, M Eric Gershwin, Zhe-Xiong Lian

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Dynamic Network Biomarker of Pre-Exhausted CD8Frontiers in immunology · 2021
    Article
  7. Animal Models of Autoimmune Liver Diseases: a Comprehensive Review.Clinical reviews in allergy & immunology · 2020
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Qing-Zhi LiuLiver Immunology Laboratory, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Wen-Tao MaLiver Immunology Laboratory, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Jing-Bo YangLiver Immunology Laboratory, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Zhi-Bin ZhaoLiver Immunology Laboratory, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Kai YanLiver Immunology Laboratory, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Yuan YaoLiver Immunology Laboratory, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Liang LiLiver Immunology Laboratory, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Qi MiaoDepartment of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
M Eric GershwinDivision of Rheumatology, Allergy and Clinical Immunology, School of Medicine, University of California, Davis, Davis, CA, United States.
Zhe-Xiong LianLiver Immunology Laboratory, School of Life Sciences, University of Science and Technology of China, Hefei, China.
South China University of Technology · CNUniversity of Science and Technology of China · CNRenji Hospital · CNUniversity of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CXC chemokine receptor 3 (CXCR3), a receptor for the C-X-C motif chemokines (CXCL) CXCL9, CXCL10, and CXCL11, which not only plays a role in chemotaxis but also regulates differentiation and development of memory and effector T cell populations. Herein, we explored the function of CXCR3 in the modulation of different organ-specific autoimmune diseases in interleukin (IL)-2 receptor deficiency (CD25

Indexed as

AnimalsAutoimmune DiseasesBiomarkersCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCholangitisColitisColonDisease Models, AnimalGene DeletionGene Expression ProfilingGene Expression RegulationInflammation MediatorsLigandsLiverMiceBiomarkersInflammation MediatorsLigandsReceptors, CXCR3autoimmune cholangitisCD4+ T cellsCD8+ T cellscolitisCXC chemokine receptor 3interferon-γinterleukin-17APD-1

Identifiers

PMID29868034
PMCPMC5966573
OpenAlexW2801247295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.