Evidence map›Paper›PMID 29868018›Full record

ArticleFrontiers in immunology2018

Fluorescent Tracking of Yeast Division Clarifies the Essential Role of Spleen Tyrosine Kinase in the Intracellular Control of

Zeina Dagher, Shuying Xu, Paige E Negoro, Nida S Khan, Michael B Feldman, Jennifer L Reedy, Jenny M Tam, David B Sykes, Michael K Mansour

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Fungistatic Effect of Phthalide Lactones onMolecules (Basel, Switzerland) · 2023
    Article
  7. Article
  8. Characterization of Virulence Factors inJournal of fungi (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Sialic Acid-Siglec-E Interactions DuringFrontiers in immunology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Zeina DagherDivision of Infectious Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Shuying XuDivision of Infectious Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Paige E NegoroDivision of Infectious Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Nida S KhanDivision of Infectious Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Michael B FeldmanDivision of Pulmonary and Critical Care, Massachusetts General Hospital, Boston, MA, United States.
Jennifer L ReedyDivision of Infectious Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Jenny M TamDivision of Infectious Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
David B SykesCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, United States.
Michael K MansourDivision of Infectious Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Harvard University · USMassachusetts General Hospital · USUniversity of Massachusetts Chan Medical School · US

Funding

INFECTIOUS DISEASE AND BASIC MICROBIOLOGICAL MECHANISMST32AI007061 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Marcia B Goldberg · 1985 to 2026
$12.1M
Research Training in Pulmonary Immunology and Allergy at MGHT32HL116275 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI David C Christiani, ANDREW D LUSTER · 2013 to 2026
$8.6M
Subcellular Mechanisms for Fungal Phagosome Maturation in MacrophagesK08AI110655 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MANSOUR, MICHAEL K · 2014 to 2017
$759k
Developing differentiation therapy for the treatment of patients with acute myeloid leukemiaK08CA201640 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI SYKES, DAVID B · 2017 to 2020
$677k
NCI NIH HHS K08 CA201640NHLBI NIH HHS T32 HL116275NIAID NIH HHS K08 AI110655NIAID NIH HHS T32 AI007061
6 · The paper itself

Abstract

Macrophages play a critical role in the elimination of fungal pathogens. They are sensed

Indexed as

Cell DivisionAnimalsBiomarkersCandida glabrataCandidiasisCell TrackingFluorescent Antibody TechniqueMacrophagesMacrophages, PeritonealMicePhagocytosisReactive Oxygen SpeciesSignal TransductionSyk KinaseBiomarkersReactive Oxygen SpeciesSyk KinaseCandidaCandida glabratacarboxyfluorescein succinimidyl estermacrophagesphagosomespleen tyrosine kinase

Identifiers

PMID29868018
PMCPMC5964189
OpenAlexW2801300567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.