Evidence map›Paper›PMID 29868013›Full record

ArticleFrontiers in immunology2018

Critical Contribution of NK Group 2 Member D Expressed on Invariant Natural Killer T Cells in Concanavalin A-Induced Liver Hepatitis in Mice.

Dina Al Dulaimi, Jihene Klibi, Veronica Olivo Pimentel, Veronique Parietti, Matthieu Allez, Antoine Toubert, Kamel Benlagha

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Dina Al DulaimiINSERM, UMR-1160, Institut Universitaire d'Hématologie, Paris, France.
Jihene KlibiINSERM, UMR-1160, Institut Universitaire d'Hématologie, Paris, France.
Veronica Olivo PimentelINSERM, UMR-1160, Institut Universitaire d'Hématologie, Paris, France.
Veronique PariettiUniversité Paris Diderot, Sorbonne Paris Cité, Paris, France.
Matthieu AllezINSERM, UMR-1160, Institut Universitaire d'Hématologie, Paris, France.
Antoine ToubertINSERM, UMR-1160, Institut Universitaire d'Hématologie, Paris, France.
Kamel BenlaghaINSERM, UMR-1160, Institut Universitaire d'Hématologie, Paris, France.
Université Paris Cité · FRDélégation Paris 7 · FRInstitut Universitaire de France · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer group 2D (NKG2D) is a well-characterized activating receptor expressed on many immune cells, including invariant natural killer T (iNKT) cells. These cells were shown to be responsible of liver injury in the model of concanavalin A (Con A)-induced hepatitis, considered to be an experimental model of human autoimmune hepatitis. In this study, we investigated whether NKG2D plays a role in the hepatitis induced by iNKT cell-mediated immune response to Con A. By using killer cell lectin-like receptor subfamily K, member 1 deficient (

Indexed as

AnimalsConcanavalin ACytokinesFas Ligand ProteinHepatitis, AnimalHepatitis, AutoimmuneHepatocytesLiverLymphocyte ActivationMiceMice, KnockoutNatural Killer T-CellsNK Cell Lectin-Like Receptor Subfamily KConcanavalin ACytokinesFas Ligand ProteinFasl protein, mouseKlrk1 protein, mouseNK Cell Lectin-Like Receptor Subfamily KcytokinesFAS-LiNKTNK-receptorsRAE-1

Identifiers

PMID29868013
PMCPMC5966527
OpenAlexW2800437202

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.