Evidence map›Paper›PMID 29867981›Full record

ArticleFrontiers in immunology2018

Non-Invasive Multiphoton Imaging of Islets Transplanted Into the Pinna of the NOD Mouse Ear Reveals the Immediate Effect of Anti-CD3 Treatment in Autoimmune Diabetes.

Robert A Benson, Fabien Garcon, Asha Recino, John R Ferdinand, Menna R Clatworthy, Herman Waldmann, James M Brewer, Klaus Okkenhaug, Anne Cooke, Paul Garside and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Robert A BensonCollege of Medical, Veterinary & Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Fabien GarconLaboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge, United Kingdom.
Asha RecinoDepartment of Pathology, University of Cambridge, Cambridge, United Kingdom.
John R FerdinandMolecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge, United Kingdom.
Menna R ClatworthyMolecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge, United Kingdom.
Herman WaldmannSir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
James M BrewerCollege of Medical, Veterinary & Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Klaus OkkenhaugLaboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge, United Kingdom.
Anne CookeDepartment of Pathology, University of Cambridge, Cambridge, United Kingdom.
Paul GarsideCollege of Medical, Veterinary & Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Maja WållbergDepartment of Pathology, University of Cambridge, Cambridge, United Kingdom.
University of Cambridge · GBUniversity of Glasgow · GBBabraham Institute · GBUniversity of Oxford · GB

Funding

Arthritis Research UK 19788Arthritis Research UK 20298Biotechnology and Biological Sciences Research Council BB/F015461/1Biotechnology and Biological Sciences Research Council BBS/E/B/000C0407Diabetes UK 13/0004785National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/M001083/1Wellcome Trust 095691
6 · The paper itself

Abstract

We present a novel and readily accessible method facilitating cellular time-resolved imaging of transplanted pancreatic islets. Grafting of islets to the mouse ear pinna allows non-invasive,

Indexed as

Islets of Langerhans TransplantationAnimalsAutoimmunityDiabetes Mellitus, Type 1Disease Models, AnimalEar AuricleIslets of LangerhansMiceMice, Inbred C57BLMice, Inbred NODMice, SCIDMice, TransgenicMicroscopy, Fluorescence, MultiphotonMuromonab-CD3T-LymphocytesTransplantation, IsogeneicMuromonab-CD3anti-CD3autoimmunityimagingimmunotherapyisletsmultiphotonT celltype 1 diabetes

Identifiers

PMID29867981
PMCPMC5968092
OpenAlexW2802284773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.