Evidence map›Paper›PMID 29867980›Full record

ArticleFrontiers in immunology2018

Semaphorin-3E Produced by Immature Dendritic Cells Regulates Activated Natural Killer Cells Migration.

Abdulaziz Alamri, Rahmat Rahman, Manli Zhang, Abeer Alamri, Abdelilah S Gounni, Sam K P Kung

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

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  15. Semaphorin Signaling in Cancer-Associated Inflammation.International journal of molecular sciences · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Abdulaziz AlamriDepartment of Immunology, University of Manitoba, Winnipeg, MB, Canada.
Rahmat RahmanDepartment of Immunology, University of Manitoba, Winnipeg, MB, Canada.
Manli ZhangDepartment of Immunology, University of Manitoba, Winnipeg, MB, Canada.
Abeer AlamriDepartment of Oral Biology, University of Manitoba, Winnipeg, MB, Canada.
Abdelilah S GounniDepartment of Immunology, University of Manitoba, Winnipeg, MB, Canada.
Sam K P KungDepartment of Immunology, University of Manitoba, Winnipeg, MB, Canada.
University of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer (NK) cells and dendritic cells (DCs) are two innate immune cells that are critical in regulating innate and adaptive immunity. Cellular functions and migratory responses of NK or DC can be further regulated in NK-DC crosstalk that involves multiple cytokine signals and/or direct cell-cell contacts. Semaphorin-3E (Sema-3E) is a member of a large family of Semaphorin proteins that play diverse regulatory functions in different biological systems upon its binding to the cognate receptors. However, possible role(s) of Sema-3E on the regulation of NK-cell functions has not been elucidated. Here, we first demonstrated that DC and NK cells expressed Sema-3E and its receptors, respectively. To formally address the importance of DC-derived Sema-3E in regulating NK-cell migration, we compared

Indexed as

Lymphocyte ActivationAnimalsCell CommunicationCells, CulturedCytoskeletal ProteinsDendritic CellsGene Expression RegulationGlycoproteinsImmunity, InnateKiller Cells, NaturalMembrane ProteinsMiceMice, Inbred BALB CMice, KnockoutSemaphorinsSignal TransductionCytoskeletal ProteinsGlycoproteinsMembrane ProteinsSema3e protein, mouseSemaphorinscell traffickingcytokines activationdendritic cellsinnate immunitynatural killer cellssemaphorinsTLR ligands

Identifiers

PMID29867980
PMCPMC5954025
OpenAlexW2799296899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.