Evidence map›Paper›PMID 29867968›Full record

ArticleFrontiers in immunology2018

Murine CMV Expressing the High Affinity NKG2D Ligand MULT-1: A Model for the Development of Cytomegalovirus-Based Vaccines.

Lea Hiršl, Ilija Brizić, Tina Jenuš, Vanda Juranić Lisnić, Johanna Julia Reichel, Slaven Jurković, Astrid Krmpotić, Stipan Jonjić

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Decoding murine cytomegalovirus.PLoS pathogens · 2023
    Article
  5. Article
  6. Review
  7. Review
  8. Rodent Models of Congenital Cytomegalovirus Infection.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Vaccine vectors: the bright side of cytomegalovirus.Medical microbiology and immunology · 2019
    Review
  14. Fuel and brake of memory T cell inflation.Medical microbiology and immunology · 2019
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lea HiršlCenter for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Ilija BrizićCenter for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Tina JenušCenter for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Vanda Juranić LisnićCenter for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Johanna Julia ReichelCenter for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Slaven JurkovićMedical Physics Department, University Hospital Rijeka, Rijeka, Croatia.
Astrid KrmpotićDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Stipan JonjićCenter for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
University of Rijeka · HR

Funding

European Research Council 322693
6 · The paper itself

Abstract

The development of a vaccine against human cytomegalovirus (CMV) has been a subject of long-term medical interest. The research during recent years identified CMV as an attractive vaccine vector against infectious diseases and tumors. The immune response to CMV persists over a lifetime and its unique feature is the inflationary T cell response to certain viral epitopes. CMV encodes numerous genes involved in immunoevasion, which are non-essential for virus growth

Indexed as

AnimalsAnimals, NewbornCarrier ProteinsCD8-Positive T-LymphocytesCytomegalovirus InfectionsCytomegalovirus VaccinesDisease Models, AnimalFemaleGenetic VectorsHistocompatibility Antigens Class IImmunity, Maternally-AcquiredImmunocompetenceKiller Cells, NaturalMembrane ProteinsMice, Inbred BALB CMice, Inbred C57BLCarrier ProteinsCytomegalovirus VaccinesHistocompatibility Antigens Class IKlrk1 protein, mouseMembrane ProteinsNK Cell Lectin-Like Receptor Subfamily KUL16 binding protein 1, mouseCD8+ T cellscytomegalovirusmurine CMVmurine UL16 binding protein-like transcript 1NK cellsNKG2Dvaccine

Identifiers

PMID29867968
PMCPMC5949336
OpenAlexW2799445495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.