Evidence map›Paper›PMID 29867965›Full record

ArticleFrontiers in immunology2018

Increased Production of IL-17A-Producing γδ T Cells in the Thymus of Filaggrin-Deficient Mice.

Mia Hamilton Jee, Jeanne Duus Johansen, Terkild Brink Buus, Trine Hilkjær Petersen, Anne-Sofie Østergaard Gadsbøll, Anders Woetmann, Niels Ødum, Jacob Pontoppidan Thyssen, Andrea Jane White, Graham Anderson and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Revisiting the Roles of Filaggrin in Atopic Dermatitis.International journal of molecular sciences · 2022
    Review
  2. Increased Th22 cell numbers in a general pediatric population with filaggrin haploinsufficiency: The Generation R Study.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2021
    Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Mia Hamilton JeeDepartment of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Jeanne Duus JohansenNational Allergy Research Centre, Department of Dermato-Allergology, Copenhagen University Hospital Gentofte, Hellerup, Denmark.
Terkild Brink BuusDepartment of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Trine Hilkjær PetersenDepartment of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Anne-Sofie Østergaard GadsbøllDepartment of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Anders WoetmannDepartment of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Niels ØdumDepartment of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Jacob Pontoppidan ThyssenNational Allergy Research Centre, Department of Dermato-Allergology, Copenhagen University Hospital Gentofte, Hellerup, Denmark.
Andrea Jane WhiteInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom.
Graham AndersonInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom.
Carsten GeislerDepartment of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Charlotte Menné BonefeldDepartment of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DKGentofte Hospital · DKUniversity of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mutations in the filaggrin gene (

Indexed as

AnimalsCell DifferentiationFilaggrin ProteinsInterleukin-17Interleukin-23Interleukin-6Intermediate Filament ProteinsMiceMice, Inbred C57BLMutationReceptors, Antigen, T-Cell, gamma-deltaSkinSpleenTh17 CellsThymus GlandFilaggrin ProteinsFLG protein, humanInterleukin-17Interleukin-23Interleukin-6interleukin-6, mouseIntermediate Filament ProteinsReceptors, Antigen, T-Cell, gamma-deltadevelopmentfilaggrinft/ft miceIL-17thymusγδ T cells

Identifiers

PMID29867965
PMCPMC5953325
OpenAlexW2802508478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.