ReviewFrontiers in immunology2018
Fish Lymphocytes: An Evolutionary Equivalent of Mammalian Innate-Like Lymphocytes?
Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 99 citations in OpenAlex.
- Modulation of Master Transcription Factor Expression of Nile Tilapia Leukocytes via Cholinergic Pathways.International journal of molecular sciences · 2025Article
- Characterization of B Cell Responses in Rainbow Trout (Oncorhynchus Mykiss) Affected by Red Mark Syndrome.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Interwoven processes in fish development: microbial community succession and immune maturation.PeerJ · 2024Review
- Transcriptionally distinct B cell profiles in systemic immune tissues and peritoneal cavity of Atlantic salmon (Frontiers in immunology · 2024Article
- Antibacterial Activity of Rainbow Trout Plasma: In Vitro Assays and Proteomic Analysis.Animals : an open access journal from MDPI · 2023Article
- Revealing theInternational journal of molecular sciences · 2023Article
- Yeast cell wall extracts fromFrontiers in immunology · 2023Article
- The thymus and T-cell ontogeny in ballan wrasse (Frontiers in immunology · 2023Article
- Functional and Phenotypic Characterization of B Cells in the Teleost Adipose Tissue.Frontiers in immunology · 2022Article
- Teleost fish IgMFrontiers in immunology · 2022Article
- Assessing Fish Immunotoxicity by Means ofFrontiers in immunology · 2022Review
- Novel Insight Into Nutritional Regulation in Enhancement of Immune Status and Mediation of Inflammation Dynamics Integrated StudyFrontiers in immunology · 2022Article
- Essential role of 4E-BP1 for lymphocyte activation and proliferation in the adaptive immune response of Nile tilapia.Fish and shellfish immunology reports · 2021Article
- Protection of Teleost Fish against Infectious Diseases through Oral Administration of Vaccines: Update 2021.International journal of molecular sciences · 2021Review
- Assessing the impacts of in-feed probiotic on the growth performance and health condition of pangasius (Aquaculture reports · 2021Article
- Molecular, Cellular and Functional Analysis of TRγ Chain along the European Sea BassInternational journal of molecular sciences · 2021Article
- Epidermal Club Cells in Fishes: A Case for Ecoimmunological Analysis.International journal of molecular sciences · 2021Review
- Immunoglobulins in teleosts.Immunogenetics · 2021Review
- CD38 Defines a Subset of B Cells in Rainbow Trout Kidney With High IgM Secreting Capacities.Frontiers in immunology · 2021Article
- Medicinal Plant Leaf Extract From Sage and Lemon Verbena Promotes Intestinal Immunity and Barrier Function in Gilthead Seabream (Frontiers in immunology · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lymphocytes are the responsible of adaptive responses, as they are classically described, but evidence shows that subpopulations of mammalian lymphocytes may behave as innate-like cells, engaging non-self rapidly and without antigen presentation. The innate-like lymphocytes of mammals have been mainly identified as γδT cells and B1-B cells, exert their activities principally in mucosal tissues, may be involved in human pathologies and their functions and tissue(s) of origin are not fully understood. Due to similarities in the morphology and immunobiology of immune system between fish and mammals, and to the uniqueness of having free-living larval stages where the development can be precisely monitored and engineered, teleost fish are proposed as an experimental model to investigate human immunity. However, the homology between fish lymphocytes and mammalian innate-like lymphocytes is an issue poorly considered in comparative immunology. Increasing experimental evidence suggests that fish lymphocytes could have developmental, morphological, and functional features in common with innate-like lymphocytes of mammals. Despite such similarities, information on possible links between conventional fish lymphocytes and mammalian innate-like lymphocytes is missing. The aim of this review is to summarize and describe available findings about the similarities between fish lymphocytes and mammalian innate-like lymphocytes, supporting the hypothesis that mammalian γδT cells and B1-B cells could be evolutionarily related to fish lymphocytes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.