Evidence map›Paper›PMID 29867942›Full record

ArticleFrontiers in immunology2018

Granulocyte-Derived Extracellular Vesicles Activate Monocytes and Are Associated With Mortality in Intensive Care Unit Patients.

Ali Danesh, Heather C Inglis, Mohamed Abdel-Mohsen, Xutao Deng, Avril Adelman, Kenneth B Schechtman, John W Heitman, Ryan Vilardi, Avani Shah, Sheila M Keating and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Review
  5. Myeloid Extracellular Vesicles: New Players in Indirect Lung Injury.American journal of respiratory cell and molecular biology · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Extracellular Vesicles Linking Inflammation, Cancer and Thrombotic Risks.Frontiers in cell and developmental biology · 2022
    Review
  11. Article
  12. Review
  13. Review
  14. Observational
  15. Article
  16. The crosstalk: exosomes and lipid metabolism.Cell communication and signaling : CCS · 2020
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Ali DaneshBlood Systems Research Institute, San Francisco, CA, United States.
Heather C InglisBlood Systems Research Institute, San Francisco, CA, United States.
Mohamed Abdel-MohsenBlood Systems Research Institute, San Francisco, CA, United States.
Xutao DengBlood Systems Research Institute, San Francisco, CA, United States.
Avril AdelmanDivision of Biostatistics, Washington University School of Medicine in St. Louis, St. Louis, MO, United States.
Kenneth B SchechtmanDivision of Biostatistics, Washington University School of Medicine in St. Louis, St. Louis, MO, United States.
John W HeitmanBlood Systems Research Institute, San Francisco, CA, United States.
Ryan VilardiDepartment of Surgery, University of California, San Francisco, San Francisco, CA, United States.
Avani ShahBlood Systems Research Institute, San Francisco, CA, United States.
Sheila M KeatingBlood Systems Research Institute, San Francisco, CA, United States.
Mitchell J CohenDepartment of Surgery, University of California, San Francisco, San Francisco, CA, United States.
Evan S JacobsBlood Systems Research Institute, San Francisco, CA, United States.
Satish K PillaiBlood Systems Research Institute, San Francisco, CA, United States.
Jacques LacroixCentre Hospitalier Universitaire (CHU) Sainte-Justine, Université de Montréal, Montreal, QC, Canada.
Philip C SpinellaDepartment of Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO, United States.
Philip J NorrisBlood Systems Research Institute, San Francisco, CA, United States.
Blood Systems Research Institute · USUniversity of California, San Francisco · USWashington University in St. Louis · USUniversité de Montréal · CA

Funding

Transfusion Medicine/Hemostasis Research Network: DCCU01HL072268 · NHLBI · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI ASSMANN, SUSAN FERA · 2002 to 2012
$33.2M
Properties of stored RBCs: minimization of immune and vascular reactivityR01HL095470 · NHLBI · VITALANT · PI NORRIS, PHILIP J. · 2009 to 2012
$2.3M
NHLBI NIH HHS R01 HL095470NHLBI NIH HHS U01 HL072268
6 · The paper itself

Abstract

To understand how extracellular vesicle (EV) subtypes differentially activate monocytes, a series of

Indexed as

Hospital MortalityIntensive Care UnitsBiomarkersCritical IllnessCytokinesExtracellular VesiclesGene Expression ProfilingGranulocyte-Macrophage Colony-Stimulating FactorGranulocytesHigh-Throughput Nucleotide SequencingHumansMacrophagesMonocytesRisk FactorsTransforming Growth Factor betaBiomarkersCytokinesGranulocyte-Macrophage Colony-Stimulating FactorTransforming Growth Factor betaexosomesextracellular vesiclesgranulocytesintensive care unitmicrovesiclesmonocytesmortalityreceptor

Identifiers

PMID29867942
PMCPMC5951932
OpenAlexW2802670047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.