Evidence map›Paper›PMID 29867930›Full record

ArticleFrontiers in immunology2018

Emerith M Hungria, Samira Bührer-Sékula, Regiane M Oliveira, Lúcio C Aderaldo, Maria Araci A Pontes, Rossilene Cruz, Heitor S de Gonçalves, Maria L F Penna, Gerson O Penna, Mariane M A Stefani

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00669643 (Independent Study to Establish the Efficacy of the Six Doses Uniform MDT Regimen), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00669643 phase4completednot on this map

Independent Study to Establish the Efficacy of the Six Doses Uniform MDT Regimen (U-MDT) for Leprosy Patients

TypeinterventionalSponsorUniversity of BrasiliaRan2007 to 2016Enrolled859ConditionsLeprosyArmsPB 6 doses - Rifampicin and Dapsone, PB 6 doses - Rifampicin, Clofazimine and Dapsone, MB 12 doses - Rifampicin, Clofazimine and Dapsone, MB 6 doses - Rifampicin, Clofazimine and Dapsone
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Glycosylation profile ofiScience · 2026
    Article
  2. Article
  3. Molecular and Serological Surveillance forAnimals : an open access journal from MDPI · 2024
    Article
  4. Challenges and advances in serological and molecular tests to aid leprosy diagnosis.Experimental biology and medicine (Maywood, N.J.) · 2023
    Review
  5. Article
  6. Detection and Monitoring ofFrontiers in microbiology · 2021
    Article
  7. Leprosy surveillance study in a highly endemic Brazilian area using leprosy specific serologic tests and IFNγ whole blood assay.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Article
  8. Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Emerith M HungriaInstituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Brazil.
Samira Bührer-SékulaInstituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Brazil.
Regiane M OliveiraInstituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Brazil.
Lúcio C AderaldoCentro de Dermatologia Dona Libânia, Fortaleza, Brazil.
Maria Araci A PontesCentro de Dermatologia Dona Libânia, Fortaleza, Brazil.
Rossilene CruzFundação de Dermatologia Tropical e Venereologia Alfredo da Matta, Manaus, Brazil.
Heitor S de GonçalvesCentro de Dermatologia Dona Libânia, Fortaleza, Brazil.
Maria L F PennaDepartamento de Epidemiologia e Bioestatística, Universidade Federal Fluminense, Rio de Janeiro, Brazil.
Gerson O PennaNúcleo de Medicina Tropical, Universidade de Brasília, e FIOCRUZ Brasília, Brasília, Brazil.
Mariane M A StefaniInstituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Brazil.
Universidade Federal de Goiás · BRInstituto de Dermatologia Dona Libania · BRFundação de Medicina Tropical · BRFundação Oswaldo Cruz · BRUniversidade Federal Fluminense · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leprosy serology reflects the bacillary load of patients and multidrug therapy (MDT) reduces Clinical Trial Registration: ClinicalTrials.gov, NCT00669643.

Indexed as

AdolescentAdultAgedAntibodies, BacterialAntigens, BacterialAntitubercular AgentsBrazilChildClofazimineDapsoneDrug Administration ScheduleDrug Therapy, CombinationEnzyme-Linked Immunosorbent AssayFemaleHumansImmunoglobulin MAntibodies, BacterialAntigens, BacterialAntitubercular AgentsClofazimineDapsoneImmunoglobulin MRifampinleprosyLID-1multidrug therapyND-O-LIDphenollic glycolipid-I antigenserology

Identifiers

PMID29867930
PMCPMC5960669
OpenAlexW2803087868

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.