ArticleFrontiers in microbiology2018
High-Temperature Short-Time Pasteurization System for Donor Milk in a Human Milk Bank Setting.
Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
30 citing papers in PubMed, 73 citations in OpenAlex.
- Trial
- Impact of microbiological testing protocols on discard rates in donor human milk with a focus onFrontiers in microbiology · 2026Article
- A Framework for Evaluation of New Processing Technologies in Human Milk Banking.Comprehensive reviews in food science and food safety · 2025Review
- Validation of a Real-Time PCR Assay for Fully Automated Detection ofMicroorganisms · 2025Article
- Article
- Evaluating continuous nanosecond pulsed electric field (nsPEF) treatment as a non-thermal alternative for human milk pasteurisation.PloS one · 2025Article
- Personalized Nutrition with Banked Human Milk for Early Gut Microbiota Development: In Pursuit of the Perfect Match.Nutrients · 2024Review
- Why could high-pressure breast milk processing improve the life of preterm babies?European journal of clinical nutrition · 2024Review
- Donor human milk: the influence of processing technologies on its nutritional and microbial composition.Frontiers in nutrition · 2024Review
- Comparative analyses of holder pasteurization vs. HTST pasteurization for donor milk: a cost-minimization study applicable to human milk banks.International breastfeeding journal · 2023Article
- Breast milk preservation: thermal and non-thermal processes and their effect on microorganism inactivation and the content of bioactive and nutritional compounds.Frontiers in nutrition · 2023Review
- Characteristics and qualities of edible bird's nest beverage as affected by thermal pasteurization and sterilization.Journal of food science and technology · 2022Article
- The hidden universe of human milk microbiome: origin, composition, determinants, role, and future perspectives.European journal of pediatrics · 2022Review
- How to Provide Breast Milk for the Preterm Infant and Avoid Symptomatic Cytomegalovirus Infection with Possible Long-Term Sequelae.Life (Basel, Switzerland) · 2022Review
- A novel heat treatment protocol for human milk.Frontiers in pediatrics · 2022Article
- Holder Pasteurization: Comparison of Water-Bath and Dry-Tempering Devices.Frontiers in pediatrics · 2022Article
- A novel continuous hydrodynamic cavitation technology for the inactivation of pathogens in milk.Ultrasonics sonochemistry · 2021Article
- High-Temperature Short-Time and Holder Pasteurization of Donor Milk: Impact on Milk Composition.Life (Basel, Switzerland) · 2021Article
- High-Temperature Short-Time Preserves Human Milk's Bioactive Proteins and Their Function Better Than Pasteurization Techniques With Long Processing Times.Frontiers in pediatrics · 2021Article
- The Revolution of Breast Milk: The Multiple Role of Human Milk Banking between Evidence and Experience-A Narrative Review.International journal of pediatrics · 2021Review
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Donor milk is the best alternative for the feeding of preterm newborns when mother's own milk is unavailable. For safety reasons, it is usually pasteurized by the Holder method (62.5°C for 30 min). Holder pasteurization results in a microbiological safe product but impairs the activity of many biologically active compounds such as immunoglobulins, enzymes, cytokines, growth factors, hormones or oxidative stress markers. High-temperature short-time (HTST) pasteurization has been proposed as an alternative for a better preservation of some of the biological components of human milk although, at present, there is no equipment available to perform this treatment under the current conditions of a human milk bank. In this work, the specific needs of a human milk bank setting were considered to design an HTST equipment for the continuous and adaptable (time-temperature combination) processing of donor milk. Microbiological quality, activity of indicator enzymes and indices for thermal damage of milk were evaluated before and after HTST treatment of 14 batches of donor milk using different temperature and time combinations and compared to the results obtained after Holder pasteurization. The HTST system has accurate and simple operation, allows the pasteurization of variable amounts of donor milk and reduces processing time and labor force. HTST processing at 72°C for, at least, 10 s efficiently destroyed all vegetative forms of microorganisms present initially in raw donor milk although sporulated
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.