Evidence map›Paper›PMID 29867785›Full record

ArticleFrontiers in microbiology2018

Arachidonic Acid Stress Impacts Pneumococcal Fatty Acid Homeostasis.

Bart A Eijkelkamp, Stephanie L Begg, Victoria G Pederick, Claudia Trapetti, Melissa K Gregory, Jonathan J Whittall, James C Paton, Christopher A McDevitt

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
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  5. Article
  6. Review
  7. Bacterial acquisition of host fatty acids has far-reaching implications on virulence.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Antifungal Peptide P852 Controls Fusarium Wilt in Faba Bean (Antioxidants (Basel, Switzerland) · 2022
    Article
  13. Review
  14. Synergistic Impact of Bioactive Byproduct Extract Leads to Anti-Journal of fungi (Basel, Switzerland) · 2021
    Article
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Bart A EijkelkampResearch Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia.
Stephanie L BeggResearch Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia.
Victoria G PederickResearch Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia.
Claudia TrapettiResearch Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia.
Melissa K GregoryAdelaide Medical School, University of Adelaide, Adelaide, SA, Australia.
Jonathan J WhittallResearch Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia.
James C PatonResearch Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia.
Christopher A McDevittResearch Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia.
University of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Free fatty acids hold dual roles during infection, serving to modulate the host immune response while also functioning directly as antimicrobials. Of particular importance are the long chain polyunsaturated fatty acids, which are not commonly found in bacterial organisms, that have been proposed to have antibacterial roles. Arachidonic acid (AA) is a highly abundant long chain polyunsaturated fatty acid and we examined its effect upon

Indexed as

antibacterial fatty acidsFASIIfree fatty acidshost lipidsmacrophagesmembrane fluidity

Identifiers

PMID29867785
PMCPMC5958418
OpenAlexW2800172462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.