Evidence map›Paper›PMID 29867746›Full record

ArticleFrontiers in neurology2018

Progressive Demyelination in the Presence of Serum Myelin Oligodendrocyte Glycoprotein-IgG: A Case Report.

Sara Gil-Perotin, Jéssica Castillo-Villalba, Joan Carreres-Polo, Arantxa Navarré-Gimeno, Javier Mallada-Frechín, Francisco Pérez-Miralles, Francisco Gascón, Carmen Alcalá-Vicente, Laura Cubas-Nuñez, Bonaventura Casanova-Estruch

Abstract readCase Reports
In one paragraph

Article in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Movement Disorders in MOGAD: A Systematic Review.Medicina (Kaunas, Lithuania) · 2026
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sara Gil-PerotinMultiple Sclerosis and Neural Regeneration Research Group, Hospital Universitari i Politècnic La Fe, València, Spain.
Jéssica Castillo-VillalbaMultiple Sclerosis and Neural Regeneration Research Group, Hospital Universitari i Politècnic La Fe, València, Spain.
Joan Carreres-PoloRadiology Department, Hospital Universitari i Politècnic La Fe, Valencia, Spain.
Arantxa Navarré-GimenoNeuroimmunology Unit, Hospital Clínic de València, Valencia, Spain.
Javier Mallada-FrechínHospital Universitari de Elda, Alicante, Spain.
Francisco Pérez-MirallesMultiple Sclerosis and Neural Regeneration Research Group, Hospital Universitari i Politècnic La Fe, València, Spain.
Francisco GascónNeuroimmunology Unit, Hospital Clínic de València, Valencia, Spain.
Carmen Alcalá-VicenteMultiple Sclerosis and Neural Regeneration Research Group, Hospital Universitari i Politècnic La Fe, València, Spain.
Laura Cubas-NuñezMultiple Sclerosis and Neural Regeneration Research Group, Hospital Universitari i Politècnic La Fe, València, Spain.
Bonaventura Casanova-EstruchMultiple Sclerosis and Neural Regeneration Research Group, Hospital Universitari i Politècnic La Fe, València, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The clinical diagnosis of patients with autoantibodies directed to conformational myelin oligodendrocyte glycoprotein MOG-IgG, can be challenging because of atypical clinical presentation. MOG-IgG seropositivity has been reported in several demyelinating diseases, including relapsing opticospinal syndromes [in the neuromyelitis optica spectrum disorders (NMOSD) and less frequently, in multiple sclerosis (MS)], but it has rarely been associated with the progressive course of disease. To contribute to the characterization of MOG-related demyelination, we describe the case of a patient with progressive demyelinating opticospinal disease, IgG-oligoclonal bands (OCB), and serum MOG-IgG.

Indexed as

cell-based assaymultiple sclerosismyelin oligodendrocyte glycoproteinNMOprogressionrecurrent inflammatory optic neuropathyspinal cord

Identifiers

PMID29867746
PMCPMC5962713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.