ArticleFrontiers in neurology2018
Alterations of Brain Structural Network in Parkinson's Disease With and Without Rapid Eye Movement Sleep Behavior Disorder.
Article in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Sleep disorders and structural alterations in brain regions linked with motivation: a neuroimaging meta-analysis.Scientific reports · 2026Pooled it
- Rapid frontotemporal gray matter loss in proposed body-first Parkinson's disease: a longitudinal voxel-based morphometry study.Frontiers in neurology · 2025Article
- Cerebellum and basal ganglia connectivity in isolated REM sleep behaviour disorder and Parkinson's disease: an exploratory study.Brain imaging and behavior · 2024Article
- Rapid eye movement sleep behavior disorder and its relation to Parkinson's disease: The potential of graph measures as brain biomarkers to identify the underlying physiopathology of the disorder.Brain and behavior · 2024Review
- Neuroanatomical findings in isolated REM sleep behavior disorder and early Parkinson's disease: a Voxel-based morphometry study.Brain imaging and behavior · 2024Article
- MRI brain structural and functional networks changes in Parkinson disease with REM sleep behavior disorders.Frontiers in aging neuroscience · 2024Article
- Functional activity, functional connectivity and complex network biomarkers of progressive hyposmia Parkinson's disease with no cognitive impairment: evidences from resting-state fMRI study.Frontiers in aging neuroscience · 2024Article
- Alteration in topological organization characteristics of gray matter covariance networks in patients with prediabetes.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2022Article
- Study on the changes of Structural Covariance Network in post-traumatic stress disorder.Brain imaging and behavior · 2022Article
- The Myelin-Weighted Connectome in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2022Article
- Alterations of Regional Homogeneity in Parkinson's Disease with Rapid Eye Movement Sleep Behavior Disorder.Neuropsychiatric disease and treatment · 2022Article
- Abnormal Gray Matter Volume and Functional Connectivity in Parkinson's Disease with Rapid Eye Movement Sleep Behavior Disorder.Parkinson's disease · 2021Article
- Reduced Gray Matter Volume and Risk of Falls in Parkinson's Disease with Dementia Patients: A Voxel-Based Morphometry Study.International journal of environmental research and public health · 2020Article
- Rapid Eye Movement Sleep Behavior Disorder and Neurodegenerative Diseases: An Update.Aging and disease · 2020Review
- [Changes of brain structural network properties in patients with rapid eye movement sleep behavior disorder].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020Article
- Altered Brain Functional Network in Parkinson Disease With Rapid Eye Movement Sleep Behavior Disorder.Frontiers in neurology · 2020Article
- Abnormal Topological Organization of Sulcal Depth-Based Structural Covariance Networks in Parkinson's Disease.Frontiers in aging neuroscience · 2020Article
- Altered Topological Properties of Brain Structural Covariance Networks in Patients With Cervical Spondylotic Myelopathy.Frontiers in human neuroscience · 2020Article
- Effectiveness of imaging genetics analysis to explain degree of depression in Parkinson's disease.PloS one · 2019Article
- Altered Intra- and Inter-regional Functional Connectivity of the Anterior Cingulate Gyrus in Patients With Tremor-Dominant Parkinson's Disease Complicated With Sleep Disorder.Frontiers in aging neuroscience · 2019Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveRapid eye movement sleep behavior disorder (RBD) has a strong association with alpha synucleinpathies such as Parkinson's disease (PD) and PD patients with RBD tend to have a poorer prognosis. However, we still know little about the pathogenesis of RBD in PD. Therefore, we aim to detect the alterations of structural correlation network (SCN) in PD patients with and without RBD. MATERIALS AND
methodsA total of 191 PD patients, including 51 patients with possible RBD (pRBD) and 140 patients with non-possible RBD, and 76 normal controls were included in the present study. Structural brain networks were constructed by thresholding gray matter volume correlation matrices of 116 regions and analyzed using graph theoretical approaches.
resultsThere was no difference in global properties among the three groups. Significant enhanced regional nodal measures in limbic system, frontal-temporal regions, and occipital regions and decreased nodal measures in cerebellum were found in PD patients with pRBD (PD-pRBD) compared with PD patients without pRBD. Besides, nodes in frontal lobe, temporal lobe, and limbic system were served as hubs in both two PD groups, and PD-pRBD exhibited additionally recruited hubs in limbic regions.
conclusionBased on the SCN analysis, we found PD-pRBD exhibited a reorganization of nodal properties as well as the remapping of the hub distribution in whole brain especially in limbic system, which may shed light to the pathophysiology of PD with RBD.
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