ArticleFrontiers in neurology2018
Reperfusion and Clinical Outcomes in Acute Ischemic Stroke: Systematic Review and Meta-Analysis of the Stent-Retriever-Based, Early Window Endovascular Stroke Trials.
Article in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- General anesthesia or conscious sedation for thrombectomy in stroke patients: an updated systematic review and meta-analysis.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023Pooled it
- CT Perfusion vs Noncontrast CT for Late Window Stroke Thrombectomy: A Systematic Review and Meta-analysis.Neurology · 2023Pooled it
- Argatroban Increased the Basal Vein Drainage and Improved Outcomes in Acute Paraventricular Ischemic Stroke Patients.Medical science monitor : international medical journal of experimental and clinical research · 2020Trial
- Impact of Anesthesia Modality on Clinical Outcomes in Anterior Circulation Stroke Patients Undergoing Mechanical Thrombectomy: A Retrospective Propensity Score-Matched Analysis.Journal of clinical medicine · 2026Article
- Management of tandem occlusions in acute ischaemic stroke.Therapeutic advances in neurological disorders · 2026Review
- The e-STROKE Study: The Design of a Prospective Observational Multicentral Study.Journal of cardiovascular development and disease · 2025Article
- Two cerebral infarctions caused by thrombus and myxomatous embolus in a patient with cardiac myxoma: A case report.Heliyon · 2024Article
- An Institutional Perspective on the Number of Stent Retriever Pass and Rate of Recanalization in Mechanical Thrombectomy for Acute Ischemic Stroke: When to Stop?Acta medica Lituanic · 2024Article
- Time to Reperfusion Is Not Associated With Functional Outcomes in First-Pass Reperfusion: Analysis of the STRATIS Registry.Stroke (Hoboken, N.J.) · 2023Article
- Factors Determining Not Returning to Full-Time Work 12 Months After Mild Ischemic Stroke.Archives of rehabilitation research and clinical translation · 2023Article
- Heterogeneous treatment effects of Cerebrolysin as an early add-on to reperfusion therapy:Frontiers in pharmacology · 2023Article
- Article
- Mechanical Thrombectomy for Acute Ischemic Stroke in Patients With Cardiac Myxoma: A Case Series and Pooled Analysis.Frontiers in neurology · 2022Article
- Article
- Balloon guide catheters: use, reject, or randomize?Neuroradiology · 2021Article
- Observational
- Endovascular therapy in patients with large vessel occlusion due to cardioembolismTherapeutic advances in neurological disorders · 2021Article
- Use of intracranial stent as rescue therapy after mechanical thrombectomy failure-9-year experience in a comprehensive stroke centre.Neuroradiology · 2020Article
- Machine learning volumetry of ischemic brain lesions on CT after thrombectomy-prospective diagnostic accuracy study in ischemic stroke patients.Neuroradiology · 2020Observational
- Safety and Efficacy of Intra-arterial Urokinase After Failed, Unsuccessful, or Incomplete Mechanical Thrombectomy in Anterior Circulation Large-Vessel Occlusion Stroke.JAMA neurology · 2020Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore the effects of reperfusion grade rates on clinical outcomes in the setting of stent-retriever-based reperfusion therapy for anterior circulation stroke in early time windows.
methodsSystematic searching of Medline and Embase databases was performed to identify stroke trials of stent-retriever-based therapy versus standard care. Mixed effects meta-regression was used to analyze the trial-level association between reperfusion rates and clinical outcomes.
resultsA total of five trials met the inclusion criteria (
conclusionIn early, stent-retriever-based acute ischemic stroke treatment, reperfusion appears to be a major predictor of outcomes. Every 10% increase in the rates of successful reperfusion is associated with an 11% increase in the probability of achieving good and 17% increase in the probability of achieving excellent outcomes. Symptomatic intracranial hemorrhage and mortality may be decreased as reperfusion rates are improved.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.