Evidence map›Paper›PMID 29867456›Full record

ReviewFrontiers in pharmacology2018

A Review on the Effect of Traditional Chinese Medicine Against Anthracycline-Induced Cardiac Toxicity.

Xinyu Yang, Nian Liu, Xinye Li, Yihan Yang, Xiaofeng Wang, Linling Li, Le Jiang, Yonghong Gao, Hebin Tang, Yong Tang and 2 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Xinyu YangGuang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing, China.
Nian LiuDepartment of Cardiology, Beijing Anzhen Hospital of the Capital University of Medical Sciences, Beijing, China.
Xinye LiGuang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing, China.
Yihan YangGuang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing, China.
Xiaofeng WangKey Laboratory of Chinese Internal Medicine of the Ministry of Education, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, China.
Linling LiDepartment of Cardiology, Beijing Anzhen Hospital of the Capital University of Medical Sciences, Beijing, China.
Le JiangDepartment of Cardiology, Beijing Anzhen Hospital of the Capital University of Medical Sciences, Beijing, China.
Yonghong GaoKey Laboratory of Chinese Internal Medicine of the Ministry of Education, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, China.
Hebin TangDepartment of Pharmacology, School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan, China.
Yong TangDepartment of Pancreatic Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Yanwei XingGuang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing, China.
Hongcai ShangKey Laboratory of Chinese Internal Medicine of the Ministry of Education, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, China.
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CNBeijing Anzhen Hospital · CNGuang’anmen Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNSouth Central University for Nationalities · CNTianjin Medical University Cancer Institute and Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anthracyclines are effective agents generally used to treat solid-tumor and hematologic malignancies. The use of anthracyclines for over 40 years has improved cancer survival statistics. Nevertheless, the clinical utility of anthracyclines is limited by its dose-dependent cardiotoxicity that adversely affects 10-30% of patients. Anthracycline-induced cardiotoxicity may be classified as acute/subacute or chronic/late toxicity and leads to devastating adverse effects resulting in poor quality of life, morbidity, and premature mortality. Traditional Chinese medicine has a history of over 2,000 years, involving both unique theories and substantial experience. Several studies have investigated the potential of natural products to decrease the cardiotoxic effects of chemotherapeutic agents on healthy cells, without negatively affecting their antineoplastic activity. This article discusses the mechanism of anthracycline-induced cardiotoxicity, and summarizes traditional Chinese medicine treatment for anthracycline-induced heart failure (HF), cardiac arrhythmia, cardiomyopathy, and myocardial ischemia in recent years, in order to provide a reference for the clinical prevention and treatment of cardiac toxicity.

Indexed as

adverse effectsanthracyclinesantineoplasticcardiac toxicitytraditional Chinese medicine

Identifiers

PMID29867456
PMCPMC5963334
OpenAlexW2803703149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.