Evidence map›Paper›PMID 29867445›Full record

ReviewFrontiers in aging neuroscience2018

Role of Ionizing Radiation in Neurodegenerative Diseases.

Neel K Sharma, Rupali Sharma, Deepali Mathur, Shashwat Sharad, Gillipsie Minhas, Kulsajan Bhatia, Akshay Anand, Sanchita P Ghosh

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in aging neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.

  1. Pooled it
  2. Radon Exposure and Neurodegenerative Disease.International journal of environmental research and public health · 2020
    Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Indian journal of clinical biochemistry : IJCB · 2025
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Modifiable contributing factors to COVID-19: A comprehensive review.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2023
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Neel K SharmaArmed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.
Rupali SharmaCenter for Neuroscience and Regenerative Medicine, Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.
Deepali MathurNeurobiology Laboratory, School of Biotechnology, KIIT University, Bhubaneswar, India.
Shashwat SharadCenter for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.
Gillipsie MinhasNeuroscience Research Lab, Department of Neurology, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Kulsajan BhatiaGovernment Medical College and Hospital, Chandigarh, India.
Akshay AnandNeuroscience Research Lab, Department of Neurology, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Sanchita P GhoshArmed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.
Uniformed Services University of the Health Sciences · USPost Graduate Institute of Medical Education and Research · INGovernment Medical College and Hospital · INKIIT University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ionizing radiation (IR) from terrestrial sources is continually an unprotected peril to human beings. However, the medical radiation and global radiation background are main contributors to human exposure and causes of radiation sickness. At high-dose exposures acute radiation sickness occurs, whereas chronic effects may persist for a number of years. Radiation can increase many circulatory, age related and neurodegenerative diseases. Neurodegenerative diseases occur a long time after exposure to radiation, as demonstrated in atomic bomb survivors, and are still controversial. This review discuss the role of IR in neurodegenerative diseases and proposes an association between neurodegenerative diseases and exposure to IR.

Indexed as

agingCNShypoxiaionizing radiationneurodegenerative diseases

Identifiers

PMID29867445
PMCPMC5963202
OpenAlexW2801658488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.