Evidence map›Paper›PMID 29867444›Full record

ArticleFrontiers in aging neuroscience2018

Brain Distribution and Modulation of Neuronal Excitability by Indicaxanthin From

Giuditta Gambino, Mario Allegra, Pierangelo Sardo, Alessandro Attanzio, Luisa Tesoriere, Maria A Livrea, Giuseppe Ferraro, Fabio Carletti

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

  1. Trial
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  9. Protective Effect of Nopal Cactus (International journal of molecular sciences · 2022
    Article
  10. Plants (Basel, Switzerland) · 2022
    Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Indicaxanthin fromAntioxidants (Basel, Switzerland) · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Giuditta GambinoDepartment of Experimental Biomedicine and Clinical Neuroscience (Bio.Ne.C.), Sezione di Fisiologia Umana G. Pagano, University of Palermo, Palermo, Italy.
Mario AllegraPost-graduate School of Nutrition and Food Science, University of Palermo, Palermo, Italy.
Pierangelo SardoDepartment of Experimental Biomedicine and Clinical Neuroscience (Bio.Ne.C.), Sezione di Fisiologia Umana G. Pagano, University of Palermo, Palermo, Italy.
Alessandro AttanzioDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Palermo, Italy.
Luisa TesoriereDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Palermo, Italy.
Maria A LivreaDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Palermo, Italy.
Giuseppe FerraroDepartment of Experimental Biomedicine and Clinical Neuroscience (Bio.Ne.C.), Sezione di Fisiologia Umana G. Pagano, University of Palermo, Palermo, Italy.
Fabio CarlettiDepartment of Experimental Biomedicine and Clinical Neuroscience (Bio.Ne.C.), Sezione di Fisiologia Umana G. Pagano, University of Palermo, Palermo, Italy.
University of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies have recently investigated the role of nutraceuticals in complex pathophysiological processes such as oxidative damages, inflammatory conditions and excitotoxicity. In this regard, the effects of nutraceuticals on basic functions of neuronal cells, such as excitability, are still poorly investigated. For this reason, the possible modulation of neuronal excitability by phytochemicals (PhC) could represent an interesting field of research given that excitotoxicity phenomena are involved in neurodegenerative alterations leading, for example, to Alzheimer's disease. The present study was focused on indicaxanthin from

Indexed as

brain localizationelectrophysiologyexcitabilityindicaxanthinmicroiontophoresisneuroprotectionnutraceuticals

Identifiers

PMID29867444
PMCPMC5954040
OpenAlexW2799660544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.