Evidence map›Paper›PMID 29867372›Full record

ArticleFrontiers in neural circuits2018

Left-Lateralized Contributions of Saccades to Cortical Activity During a One-Back Word Recognition Task.

Yu-Cherng C Chang, Sheraz Khan, Samu Taulu, Gina Kuperberg, Emery N Brown, Matti S Hämäläinen, Simona Temereanca

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neural circuits, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Correcting MEG Artifacts Caused by Overt Speech.Frontiers in neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Yu-Cherng C ChangAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States.
Sheraz KhanAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States.
Samu TauluInstitute for Learning and Brain Sciences, University of Washington, Seattle, WA, United States.
Gina KuperbergAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States.
Emery N BrownDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, United States.
Matti S HämäläinenAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States.
Simona TemereancaAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States.
Athinoula A. Martinos Center for Biomedical Imaging · USMassachusetts General Hospital · USHarvard University · USTufts University · USUniversity of Washington · US

Funding

Project 4P41EB015896 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2012 to 2018
$9.8M
Dynamic Inverse Solutions for Multimodal ImagingR01EB006385 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI BOAS, DAVID A · 2007 to 2011
$6.7M
The neural basis of language comprehension: Insights from spatiotemporal imagingR01HD082527 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI GINA R KUPERBERG · 2015 to 2026
$5.8M
Tools for Large-Scale Platform-Independent MEG Data AnalysisR01EB009048 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI HAMALAINEN, MATTI, LEAHY, RICHARD M · 2009 to 2016
$4.6M
Redesigning General Anesthesia (Admin Supp)R01GM104948 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BOYDEN, EDWARD S., BROWN, EMERY N · 2012 to 2016
$4.4M
A Systems Neuroscience Approach for the Study of General AnesthesiaDP1OD003646 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI BROWN, EMERY N · 2007 to 2011
$4.4M
A MEG Study of Saccardic Eye Movement Effects on Word ProcessingR03HD050627 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI TEMEREANCA IBANESCU, SIMONA · 2006 to 2007
$172k
NIBIB NIH HHS P41 EB015896NIBIB NIH HHS R01 EB006385NIBIB NIH HHS R01 EB009048NICHD NIH HHS R01 HD082527NICHD NIH HHS R03 HD050627NIGMS NIH HHS R01 GM104948NIH HHS DP1 OD003646
6 · The paper itself

Abstract

Saccadic eye movements are an inherent component of natural reading, yet their contribution to information processing at subsequent fixation remains elusive. Here we use anatomically-constrained magnetoencephalography (MEG) to examine cortical activity following saccades as healthy human subjects engaged in a one-back word recognition task. This activity was compared with activity following external visual stimulation that mimicked saccades. A combination of procedures was employed to eliminate saccadic ocular artifacts from the MEG signal. Both saccades and saccade-like external visual stimulation produced early-latency responses beginning ~70 ms after onset in occipital cortex and spreading through the ventral and dorsal visual streams to temporal, parietal and frontal cortices. Robust differential activity following the onset of saccades vs. similar external visual stimulation emerged during 150-350 ms in a left-lateralized cortical network. This network included: (i) left lateral occipitotemporal (LOT) and nearby inferotemporal (IT) cortex; (ii) left posterior Sylvian fissure (PSF) and nearby multimodal cortex; and (iii) medial parietooccipital (PO), posterior cingulate and retrosplenial cortices. Moreover, this left-lateralized network colocalized with word repetition priming effects. Together, results suggest that central saccadic mechanisms influence a left-lateralized language network in occipitotemporal and temporal cortex above and beyond saccadic influences at preceding stages of information processing during visual word recognition.

Indexed as

AdultBrain MappingCerebral CortexFemaleFrontal LobeHumansMagnetoencephalographyMalePhotic StimulationReadingSaccadesVision, OcularVisual PerceptionYoung Adultmagnetoencephalographyreadingsaccadesvisual motionvisual word recognition

Identifiers

PMID29867372
PMCPMC5964218
OpenAlexW2894781568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.