ArticleFrontiers in cellular neuroscience2018
Disruption of the Microglial ADP Receptor P2Y
Article in Frontiers in cellular neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 44 citations in OpenAlex.
- Purinergic Receptor P2Y2 Regulates Neurogenesis and Functional Recovery Following Spinal Cord Injury in Zebrafish.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- The P2Y13 receptor-mediated microglial morphological transformation through the p38MAPK signaling pathway contributes to central sensitization in a murine model of chronic migraine.The journal of headache and pain · 2025Article
- Genetic patterning in hippocampus of rat undergoing impaired spatial memory induced by long-term heat stress.Heliyon · 2024Article
- Differently expression of the metabotropic P2Y receptor family after hypoxia-induced seizures in neonates and seizure suppression via P2YPurinergic signalling · 2024Article
- "Sentinel or accomplice": gut microbiota and microglia crosstalk in disorders of gut-brain interaction.Protein & cell · 2023Review
- Article
- Corrigendum: Purinergic signaling systems across comparative models of spinal cord injury.Neural regeneration research · 2023Article
- Neuroglia Cells Transcriptomic in Brain Development, Aging and Neurodegenerative Diseases.Aging and disease · 2023Review
- Purinergic signaling systems across comparative models of spinal cord injury.Neural regeneration research · 2022Review
- Microglia-dependent remodeling of neuronal circuits.Journal of neurochemistry · 2022Review
- Microglial control of neuronal development via somatic purinergic junctions.Cell reports · 2022Article
- Genetics and Brain Transcriptomics of Completed Suicide.The American journal of psychiatry · 2022Article
- Article
- Cocaine induces paradigm-specific changes to the transcriptome within the ventral tegmental area.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Article
- HIV-Associated Apathy/Depression and Neurocognitive Impairments Reflect Persistent Dopamine Deficits.Cells · 2021Review
- The roles of microglia in viral encephalitis: from sensome to therapeutic targeting.Cellular & molecular immunology · 2021Review
- Botanical Drug Puerarin Ameliorates Liposaccharide-Induced Depressive Behaviors in Mice via Inhibiting RagA/mTOR/p70S6K Pathways.Oxidative medicine and cellular longevity · 2021Article
- The Potential Role of Inflammation in Modulating Endogenous Hippocampal Neurogenesis After Spinal Cord Injury.Frontiers in neuroscience · 2021Review
- The Contribution of Microglia to the Development and Maturation of the Visual System.Frontiers in cellular neuroscience · 2021Article
- Update of P2Y receptor pharmacology: IUPHAR Review 27.British journal of pharmacology · 2020Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In mammalian species, including humans, the hippocampal dentate gyrus (DG) is a primary region of adult neurogenesis. Aberrant adult hippocampal neurogenesis is associated with neurological pathologies. Understanding the cellular mechanisms controlling adult hippocampal neurogenesis is expected to open new therapeutic strategies for mental disorders. Microglia is intimately associated with neural progenitor cells in the hippocampal DG and has been implicated, under varying experimental conditions, in the control of the proliferation, differentiation and survival of neural precursor cells. But the underlying mechanisms remain poorly defined. Using fluorescent
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.