ArticleFrontiers in cellular neuroscience2018
Permanent Whisker Removal Reduces the Density of c-Fos+ Cells and the Expression of Calbindin Protein, Disrupts Hippocampal Neurogenesis and Affects Spatial-Memory-Related Tasks.
Article in Frontiers in cellular neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Comprehensive Behavioural Analysis of Rats Received Repetitive Tactile Stimulation During the Periadolescent Period.Annals of neurosciences · 2025Article
- Deprivation-Induced Plasticity in the Early Central Circuits of the Rodent Visual, Auditory, and Olfactory Systems.eNeuro · 2024Review
- The ventricular-subventricular, subgranular and subcallosal zones: three niches of neural stem cells in the postnatal brain.Experimental brain research · 2023Review
- Divergent Spatial Learning, Enhanced Neuronal Transcription, and Blood-Brain Barrier Disruption Develop During Recovery from Post-Injury Sleep Fragmentation.Neurotrauma reports · 2023Article
- Tactile information from the vibrissal system modulates hippocampal functioning.Current research in neurobiology · 2022Article
- Sensory Experience as a Regulator of Structural Plasticity in the Developing Whisker-to-Barrel System.Frontiers in cellular neuroscience · 2021Article
- Tactile modulation of memory and anxiety requires dentate granule cells along the dorsoventral axis.Nature communications · 2020Article
- Cytosolic CaCold Spring Harbor perspectives in biology · 2020Review
- Cyclohexane Inhalation Produces Long-Lasting Alterations in the Hippocampal Integrity and Reward-Seeking Behavior in the Adult Mouse.Cellular and molecular neurobiology · 2019Article
- Aberrant Somatosensory Processing and Connectivity in Mice LackingThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- The Effect of Involuntary Tactile Stimulation on the Creativity and Rey Auditory-Verbal Memory of Young Adults.Basic and clinical neuroscienceArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Facial vibrissae, commonly known as whiskers, are the main sensitive tactile system in rodents. Whisker stimulation triggers neuronal activity that promotes neural plasticity in the barrel cortex (BC) and helps create spatial maps in the adult hippocampus. Moreover, activity-dependent inputs and calcium homeostasis modulate adult neurogenesis. Therefore, the neuronal activity of the BC possibly regulates hippocampal functions and neurogenesis. To assess whether tactile information from facial whiskers may modulate hippocampal functions and neurogenesis, we permanently eliminated whiskers in CD1 male mice and analyzed the effects in cellular composition, molecular expression and memory processing in the adult hippocampus. Our data indicated that the permanent deprivation of whiskers reduced in 4-fold the density of c-Fos+ cells (a calcium-dependent immediate early gene) in
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