ArticleScientific reports2018
Effective thresholds for reporting suspicions and improve early detection of avian influenza outbreaks in layer chickens.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 36 citations in OpenAlex.
- A risk prediction model for HPAI outbreaks in Kuwait.Frontiers in veterinary science · 2026Article
- Effective mortality thresholds for reporting suspicion of highly pathogenic avian influenza in mule ducks.Veterinary research · 2025Article
- Optimizing contact tracing for avian influenza in poultry flocks.Journal of the Royal Society, Interface · 2025Article
- Assessing stakeholder inclusion within high pathogenicity avian influenza risk governance strategies in the United Kingdom and United States.Frontiers in veterinary science · 2025Article
- Quantitative Risk Assessment of Wind-Supported Transmission of Highly Pathogenic Avian Influenza Virus to Dutch Poultry Farms via Fecal Particles from Infected Wild Birds in the Environment.Pathogens (Basel, Switzerland) · 2024Article
- Vaccination of poultry against highly pathogenic avian influenza - Part 2. Surveillance and mitigation measures.EFSA journal. European Food Safety Authority · 2024Article
- Comparison of the Clinical Manifestation of HPAI H5Nx in Different Poultry Types in the Netherlands, 2014-2022.Pathogens (Basel, Switzerland) · 2024Article
- Exploring Options for Syndromic Surveillance in Aquaculture: Outbreak Detection of Salmon Pancreas Disease Using Production Data from Norwegian Farms.Transboundary and emerging diseases · 2024Article
- Age is a determinant factor in the susceptibility of domestic ducks to H5 clade 2.3.2.1c and 2.3.4.4e high pathogenicity avian influenza viruses.Frontiers in veterinary science · 2023Article
- Avian influenza overview March - June 2022.EFSA journal. European Food Safety Authority · 2022Article
- Avian influenza overview December 2021 - March 2022.EFSA journal. European Food Safety Authority · 2022Article
- Mortality Levels and Production Indicators for Suspicion of Highly Pathogenic Avian Influenza Virus Infection in Commercially Farmed Ducks.Pathogens (Basel, Switzerland) · 2021Article
- Neuraminidase-associated plasminogen recruitment enables systemic spread of natural avian Influenza viruses H3N1.PLoS pathogens · 2021Article
- Differential mitochondrial proteomic analysis of A549 cells infected with avian influenza virus subtypes H5 and H9.Virology journal · 2021Article
- Seasonal risk of low pathogenic avian influenza virus introductions into free-range layer farms in the Netherlands.Transboundary and emerging diseases · 2021Article
- Scientific Opinion on the assessment of the control measures of the category A diseases of Animal Health Law: Highly Pathogenic Avian Influenza.EFSA journal. European Food Safety Authority · 2021Article
- Highly pathogenic avian influenza subtype H5Nx clade 2.3.4.4 outbreaks in Dutch poultry farms, 2014-2018: Clinical signs and mortality.Transboundary and emerging diseases · 2021Article
- Avian Viruses that Impact Table Egg Production.Animals : an open access journal from MDPI · 2020Review
- Estimating the introduction time of highly pathogenic avian influenza into poultry flocks.Scientific reports · 2020Article
- Quantification of visits of wild fauna to a commercial free-range layer farm in the Netherlands located in an avian influenza hot-spot area assessed by video-camera monitoring.Transboundary and emerging diseases · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study was to identify effective reporting thresholds for suspicions of both highly pathogenic (HPAI) and low pathogenic avian influenza (LPAI) outbreaks in layer farms. Daily mortality and egg-production data from 30 Dutch farms with no record of AI infection were analysed and thresholds set. Mortality rates above or egg-production below these thresholds for two consecutive days would trigger an alarm sign. The following thresholds were identified for mortality: (i) A mortality threshold of 0.08% or 0.13% for layers kept indoors or with free-range access respectively, (ii) a 2.9 times higher mortality than the average weekly mortality of the previous week, and iii) a moving-average threshold that could be implemented for each specific farm. For egg-production: (i) a weekly ratio lower than 0.94 in egg-production drop, and (ii) a moving-average threshold. The accuracy of these thresholds was assessed by quantifying their sensitivity, specificity and time to trigger disease detection using data from 15 infected and 31 non-infected farms. New thresholds were more sensitive and signalled infection two to six days earlier than the presently used thresholds. A high Specificity (97-100%) was obtained by combining mortality and egg production thresholds in a serial approach to trigger an alarm.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.