ArticleScientific reports2018
Sensations from a single M-cone depend on the activity of surrounding S-cones.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 44 citations in OpenAlex.
- Article
- Local variations in L/M ratio influence the detection and color naming of small spots.Journal of vision · 2025Article
- Local variations in L/M ratio influence the detection and color naming of small spots.bioRxiv : the preprint server for biology · 2025Article
- Asymmetric activation of retinal ON and OFF pathways by AOSLO raster-scanned visual stimuli.Biomedical optics express · 2025Article
- Optogenetic Stimulation of Single Ganglion Cells in the Living Primate Fovea.bioRxiv : the preprint server for biology · 2025Article
- Novel color via stimulation of individual photoreceptors at population scale.Science advances · 2025Article
- Color appearance and the end of Hering's Opponent-Colors Theory.Trends in cognitive sciences · 2023Review
- Adaptive Optics Imaging of Inherited Retinal Disease.Cold Spring Harbor perspectives in medicine · 2023Review
- Retinal imaging using adaptive optics optical coherence tomography with fast and accurate real-time tracking.Biomedical optics express · 2022Article
- Intermixing theGenes · 2021Review
- Promises and pitfalls of evaluating photoreceptor-based retinal disease with adaptive optics scanning light ophthalmoscopy (AOSLO).Progress in retinal and eye research · 2021Review
- Dissociation between red and white stimulus perception: A perimetric quantification of protanopic color vision deficiencies.PloS one · 2021Article
- Effect of cone spectral topography on chromatic detection sensitivity.Journal of the Optical Society of America. A, Optics, image science, and vision · 2020Article
- Photopigment genes, cones, and color update: disrupting the splicing code causes a diverse array of vision disorders.Current opinion in behavioral sciences · 2019Article
- Color, Pattern, and the Retinal Cone Mosaic.Current opinion in behavioral sciences · 2019Article
- Article
- An S-cone circuit for edge detection in the primate retina.Scientific reports · 2019Article
- Probing Computation in the Primate Visual System at Single-Cone Resolution.Annual review of neuroscience · 2019Review
- Transverse chromatic offsets with pupil displacements in the human eye: sources of variability and methods for real-time correction.Biomedical optics express · 2019Article
- Reconciling Color Vision Models With Midget Ganglion Cell Receptive Fields.Frontiers in neuroscience · 2019Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Color vision requires the activity of cone photoreceptors to be compared in post-receptoral circuitry. Decades of psychophysical measurements have quantified the nature of these comparative interactions on a coarse scale. How such findings generalize to a cellular scale remains unclear. To answer that question, we quantified the influence of surrounding light on the appearance of spots targeted to individual cones. The eye's aberrations were corrected with adaptive optics and retinal position was precisely tracked in real-time to compensate for natural movement. Subjects reported the color appearance of each spot. A majority of L-and M-cones consistently gave rise to the sensation of white, while a smaller group repeatedly elicited hue sensations. When blue sensations were reported they were more likely mediated by M- than L-cones. Blue sensations were elicited from M-cones against a short-wavelength light that preferentially elevated the quantal catch in surrounding S-cones, while stimulation of the same cones against a white background elicited green sensations. In one of two subjects, proximity to S-cones increased the probability of blue reports when M-cones were probed. We propose that M-cone increments excited both green and blue opponent pathways, but the relative activity of neighboring cones favored one pathway over the other.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.