Evidence map›Paper›PMID 29867045›Full record

ArticleNutrients2018

Vitamin D₃ Status and the Association with Human Cathelicidin Expression in Patients with Different Clinical Forms of Active Tuberculosis.

Senait Ashenafi, Jolanta Mazurek, Anders Rehn, Beede Lemma, Getachew Aderaye, Amsalu Bekele, Getachew Assefa, Menberework Chanyalew, Abraham Aseffa, Jan Andersson and 2 more

Open access · goldAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Vitamin D3 InhibitsFrontiers in cellular and infection microbiology · 2020
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Senait AshenafiCenter for Infectious Medicine (CIM), F59, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden. senait.ashenafi.betemariam@ki.se.
Jolanta MazurekCenter for Infectious Medicine (CIM), F59, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden. jolanta.mazurek@gmx.com.
Anders RehnCenter for Infectious Medicine (CIM), F59, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden. anders.rehn@bredband2.com.
Beede LemmaDepartment of Surgery, Faculty of Medicine, Black Lion University Hospital and Addis Ababa University, P.O Box: 28287/1000, Addis Ababa, Ethiopia. bedelemma@yahoo.com.
Getachew AderayeDepartment of Internal Medicine, Faculty of Medicine, Black Lion University Hospital and Addis Ababa University, P.O Box: 28287/1000, Addis Ababa, Ethiopia. getadera@yahoo.com.
Amsalu BekeleDepartment of Internal Medicine, Faculty of Medicine, Black Lion University Hospital and Addis Ababa University, P.O Box: 28287/1000, Addis Ababa, Ethiopia. amsalubekele2016@gmail.com.
Getachew AssefaDepartment of Radiology, Faculty of Medicine, Black Lion University Hospital and Addis Ababa University, P.O Box: 28287/1000, Addis Ababa, Ethiopia. g_asefa@yahoo.com.
Menberework ChanyalewArmauer Hansen Research Institute (AHRI), P.O. Box 1005, Addis Ababa, Ethiopia. menberework@gmail.com.ORCID 0000-0002-4154-2100
Abraham AseffaArmauer Hansen Research Institute (AHRI), P.O. Box 1005, Addis Ababa, Ethiopia. aseffaa@gmail.com.
Jan AnderssonCenter for Infectious Medicine (CIM), F59, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden. jan.andersson@ki.se.
Peter BergmanDepartment of Laboratory Medicine (Labmed), Division of Clinical Microbiology, Karolinska Institutet, 141 86 Stockholm, Sweden. peter.bergman@ki.se.
Susanna BrighentiCenter for Infectious Medicine (CIM), F59, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden. susanna.brighenti@ki.se.
Karolinska University Hospital · SETikur Anbessa Hospital · ETArmauer Hansen Research Institute · ETKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low vitamin D (vitD₃) is one of the most common nutritional deficiencies in the world known to be associated with numerous medical conditions including infections such as tuberculosis (TB). In this study, vitD₃ status and its association with the antimicrobial peptide, human cathelicidin (LL-37), was investigated in Ethiopian patients with different clinical forms of TB. Patients with active TB (

Indexed as

AdolescentAdultAgedAntimicrobial Cationic PeptidesBiomarkersCalcifediolCase-Control StudiesCathelicidinsEthiopiaFemaleHumansMaleMiddle AgedRNA, MessengerSwedenTuberculosis, Lymph NodeAntimicrobial Cationic PeptidesBiomarkersCalcifediolCathelicidinsRNA, MessengerantimicrobialclinicalLL-37tuberculosisvitamin D

Identifiers

PMID29867045
PMCPMC6024873
OpenAlexW2806717536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.