Evidence map›Paper›PMID 29866877›Full record

ArticleAntimicrobial agents and chemotherapy2018

Pharmacodynamic and Immunomodulatory Effects of Micafungin on Host Responses against Biofilms of Candida parapsilosis in Comparison to Those of Candida albicans.

Maria Simitsopoulou, Katerina Chlichlia, Daniela Kyrpitzi, Thomas J Walsh, Emmanuel Roilides

Open access · bronzeAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Osteoarticular Mycoses.Clinical microbiology reviews · 2022
    Review
  6. How Biofilm Growth AffectsFrontiers in microbiology · 2020
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Maria SimitsopoulouLaboratory of Infectious Diseases, 3rd Department of Pediatrics, Aristotle University School of Medicine, Hippokration Hospital, Thessaloniki, Greece.
Katerina ChlichliaLaboratory of Molecular Immunobiology, Department of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis, Greece.
Daniela KyrpitziLaboratory of Infectious Diseases, 3rd Department of Pediatrics, Aristotle University School of Medicine, Hippokration Hospital, Thessaloniki, Greece.
Thomas J WalshTransplantation-Oncology Infectious Diseases Program, Weill Cornell University Medical Center, New York, New York, USA.
Emmanuel RoilidesLaboratory of Infectious Diseases, 3rd Department of Pediatrics, Aristotle University School of Medicine, Hippokration Hospital, Thessaloniki, Greece roilides@med.auth.gr.ORCID 0000-0002-0202-364X
Hippocration General Hospital · GRCornell University · USDemocritus University of Thrace · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Micafungin (MFG) demonstrates potent activity against biofilms of

Indexed as

Antifungal AgentsBiofilmsCandida albicansCandida parapsilosisCell SurvivalCoculture TechniquesGene Expression RegulationHost-Pathogen InteractionsHumansInterleukin-1betaInterleukin-23Interleukin-8MicafunginMicrobial Sensitivity TestsNeutrophilsSignal TransductionAntifungal AgentsCXCL8 protein, humanIL1B protein, humanInterleukin-1betaInterleukin-23Interleukin-8MicafunginTLR2 protein, humanTLR4 protein, humanToll-Like Receptor 2Toll-Like Receptor 4Transcription Factor RelAantibiofilm activityCandida biofilmsimmunomodulationmicafungin

Identifiers

PMID29866877
PMCPMC6105855
OpenAlexW2806707641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.