Evidence map›Paper›PMID 29866870›Full record

ArticleAntimicrobial agents and chemotherapy2018

J Chandra, L Long, N Isham, P K Mukherjee, G DiSciullo, K Appelt, M A Ghannoum

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. The In Vitro Ability ofPathogens (Basel, Switzerland) · 2021
    Article
  7. ACS applied materials & interfaces · 2021
    Article
  8. Article
  9. TheInternational journal of molecular sciences · 2021
    Article
  10. Article
  11. Journal of fungi (Basel, Switzerland) · 2019
    Review
  12. Article
  13. Antifungal activity of magnoflorine against Candida strains.World journal of microbiology & biotechnology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

J ChandraCenter for Medical Mycology, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
L LongCenter for Medical Mycology, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
N IshamCenter for Medical Mycology, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
P K MukherjeeCenter for Medical Mycology, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
G DiSciulloPrevacept Infection Control, Inc., Broomfield, Colorado, USA.
K AppeltPrevacept Infection Control, Inc., Broomfield, Colorado, USA.
M A GhannoumCenter for Medical Mycology, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA mahmoud.ghannoum@case.edu.
University Hospitals of Cleveland · USCase Western Reserve University · US

Funding

Mechanism of antifungal action of Pichia proteinsR01DE024228 · NIDCR · CASE WESTERN RESERVE UNIVERSITY · PI GHANNOUM, MAHMOUD A · 2014 to 2018
$2.0M
NIDCR NIH HHS R01 DE024228
6 · The paper itself

Abstract

Central-line-associated bloodstream infections are increasingly recognized to be associated with intraluminal microbial biofilms, and effective measures for the prevention and treatment of bloodstream infections remain lacking. This report evaluates a new commercially developed antimicrobial catheter lock solution (ACL), containing trimethoprim (5 mg/ml), ethanol (25%), and calcium EDTA (Ca-EDTA) (3%), for activity against bacterial and fungal biofilms, using

Indexed as

Anti-Bacterial AgentsAntifungal AgentsBacteriaBiofilmsCandida albicansEnterococcusMicroscopy, Electron, ScanningAnti-Bacterial AgentsAntifungal Agentsbacterial biofilmscatheter lockfungal biofilms

Identifiers

PMID29866870
PMCPMC6105826
OpenAlexW2952920484

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.