ArticleProceedings of the National Academy of Sciences of the United States of America2018
Human midcingulate cortex encodes distributed representations of task progress.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 58 citations in OpenAlex.
- Article
- Neural and computational mechanisms of effort under the pressure of a deadline.Nature communications · 2026Article
- Dorsomedial prefrontal cortex links abstract planning to motor execution.Communications biology · 2026Article
- Brain network efficiency during social interaction is associated with real-world social network size.Behavioral and brain functions : BBF · 2025Article
- Deep Learning of Brain-Behavior Dimensions Identifies Transdiagnostic Biotypes in Youth with ADHD and Anxiety Disorders.bioRxiv : the preprint server for biology · 2025Article
- ACC representations of reward-driven motivation over hierarchically-organized behavior.NeuroImage · 2025Article
- The neurocognitive mechanism underlying math avoidance among math anxious people.NPJ science of learning · 2025Article
- Neural substrates underlying multisensory stiffness perception via active touch and dynamic visual feedback.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Broadscale dampening of uncertainty adjustment in the aging brain.Nature communications · 2024Article
- Alpha and theta band activity share information relevant to proactive and reactive control during conflict-modulated response inhibition.Human brain mapping · 2023Article
- Investigating the Neural Bases of Risky Decision Making Using Multi-Voxel Pattern Analysis.Brain sciences · 2022Article
- Resting-State Functional Connectivity Impairment in Patients with Major Depressive Episode.International journal of environmental research and public health · 2022Article
- Review
- Theta oscillations shift towards optimal frequency for cognitive control.Nature human behaviour · 2022Article
- Formalizing planning and information search in naturalistic decision-making.Nature neuroscience · 2021Review
- Neural Coding of Cognitive Control: The Representational Similarity Analysis Approach.Trends in cognitive sciences · 2021Review
- A Hierarchy of Functional States in Working Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- A global framework for a systemic view of brain modeling.Brain informatics · 2021Article
- Supraspinal Mechanisms Underlying Ocular Pain.Frontiers in medicine · 2021Review
- Hierarchical Representation of Multistep Tasks in Multiple-Demand and Default Mode Networks.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The function of midcingulate cortex (MCC) remains elusive despite decades of investigation and debate. Complicating matters, individual MCC neurons respond to highly diverse task-related events, and MCC activation is reported in most human neuroimaging studies employing a wide variety of task manipulations. Here we investigate this issue by applying a model-based cognitive neuroscience approach involving neural network simulations, functional magnetic resonance imaging, and representational similarity analysis. We demonstrate that human MCC encodes distributed, dynamically evolving representations of extended, goal-directed action sequences. These representations are uniquely sensitive to the stage and identity of each sequence, indicating that MCC sustains contextual information necessary for discriminating between task states. These results suggest that standard univariate approaches for analyzing MCC function overlook the major portion of task-related information encoded by this brain area and point to promising new avenues for investigation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.