Evidence map›Paper›PMID 29866810›Full record

ArticleJournal of bacteriology2018

Combined Drug Resistance Mutations Substantially Enhance Enzyme Production in Paenibacillus agaridevorans.

Kazumi Funane, Yukinori Tanaka, Takeshi Hosaka, Kiriko Murakami, Takatsugu Miyazaki, Yuh Shiwa, Shigehachi Gibu, Takashi Inaoka, Ken Kasahara, Nobuyuki Fujita and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Kazumi Funane *Faculty of Life and Environmental Sciences, University of Yamanashi, Kofu, Yamanashi, Japan.
Yukinori Tanaka *Department of Life Sciences, Hiroshima Institute of Technology, Hiroshima, Japan.
Takeshi HosakaInstitute for Biomedical Science, Shinshu University, Nagano, Japan.
Kiriko MurakamiChitose Laboratory Co., Nogawa, Kawasaki, Japan.
Takatsugu MiyazakiFood Research Institute, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, Japan.
Yuh ShiwaFaculty of Life Sciences, Tokyo University of Agriculture, Tokyo, Japan.
Shigehachi GibuNisshin Sugar Co., Ltd., Tokyo, Japan.
Takashi InaokaFood Research Institute, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, Japan.
Ken KasaharaChitose Laboratory Co., Nogawa, Kawasaki, Japan.
Nobuyuki FujitaFaculty of Life Sciences, Tokyo University of Agriculture, Tokyo, Japan.
Hirofumi YoshikawaFaculty of Life Sciences, Tokyo University of Agriculture, Tokyo, Japan.
Yoshikazu HiragaDepartment of Life Sciences, Hiroshima Institute of Technology, Hiroshima, Japan.
Kozo OchiDepartment of Life Sciences, Hiroshima Institute of Technology, Hiroshima, Japan k.ochi.bz@it-hiroshima.ac.jp.
Hiroshima Institute of Technology · JPTokyo University of Agriculture · JPChitose Institute of Science and Technology · JPNational Agriculture and Food Research Organization · JPShinshu University · JPShizuoka University · JPUniversity of Yamanashi · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study shows that sequential introduction of drug resistance mutations substantially increased enzyme production in

Indexed as

Anti-Bacterial AgentsDrug Resistance, Multiple, BacterialGenetic EngineeringGlucosyltransferasesMetabolomeMutationPaenibacillusProtein BiosynthesisRifampinStreptomycinAnti-Bacterial Agentscycloisomaltooligosaccharide glucanotransferaseGlucosyltransferasesRifampinStreptomycindrug resistanceenzyme productionmetabolome analysisribosome engineeringsilent genes

Identifiers

PMID29866810
PMCPMC6088162
OpenAlexW2807607280

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.