ArticleJournal of the American Society of Nephrology : JASN2018
Epithelial and Endothelial Pannexin1 Channels Mediate AKI.
Erratum issuedOpen access · bronzeAbstract read
In one paragraph
Article in Journal of the American Society of Nephrology : JASN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 44 papers.
0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 53 citations in OpenAlex.
- Inhibition of (interstitial) P2YPflugers Archiv : European journal of physiology · 2026Article
- Inhibition of (interstitial) P2YResearch square · 2026Article
- Connexin 43 and Pannexin 1 in Renal Cell Populations in Diabetic Kidney Disease.International journal of molecular sciences · 2026Article
- Ultrastructural Characterization of Pannexin 1 Expression Along the Rat Nephron.International journal of molecular sciences · 2026Article
- Inhibition of (interstitial) P2YbioRxiv : the preprint server for biology · 2026Article
- Probenecid protects against contrast-induced nephropathy through modulation of small Rho GTPases and Pannexin1 channels in Wistar rats.Clinical and experimental nephrology · 2025Article
- Pannexin channels in the kidney.American journal of physiology. Renal physiology · 2025Review
- Nanobody-based Pannexin1 channel inhibitors increase survival after cardiac ischemia/reperfusion.Cell and tissue research · 2025Article
- Noncanonical function of Pannexin1 promotes cellular senescence and renal fibrosis post-acute kidney injury.Nature communications · 2025Article
- Proximal tubule pannexin 1 contributes to mitochondrial dysfunction and cell death during acute kidney injury.American journal of physiology. Renal physiology · 2025Article
- Purinoreceptor P2X7 in Extracellular ATP-Mediated Inflammation through the Spectrum of Kidney Diseases and Kidney Transplantation.Journal of the American Society of Nephrology : JASN · 2025Review
- Role of Pannexin 1, P2X7, and CFTR in ATP Release and Autocrine Signaling by Principal Cells of the Epididymis.Function (Oxford, England) · 2025Article
- Pannexin channels in inflammation and tumorigenesis.Frontiers in cell and developmental biology · 2025Review
- Pannexins in the musculoskeletal system: new targets for development and disease progression.Bone research · 2024Review
- Role of perivascular cells in kidney homeostasis, inflammation, repair and fibrosis.Nature reviews. Nephrology · 2023Review
- Emerging significance and therapeutic targets of ferroptosis: a potential avenue for human kidney diseases.Cell death & disease · 2023Review
- Pannexin1: insight into inflammatory conditions and its potential involvement in multiple organ dysfunction syndrome.Frontiers in immunology · 2023Review
- Hypertensive Nephropathy: Unveiling the Possible Involvement of Hemichannels and Pannexons.International journal of molecular sciences · 2022Review
- Targeting Ferroptosis as a Promising Therapeutic Strategy for Ischemia-Reperfusion Injury.Antioxidants (Basel, Switzerland) · 2022Review
- Sphingosine 1-phosphate signaling in perivascular cells enhances inflammation and fibrosis in the kidney.Science translational medicine · 2022Article
Corrections and comments
- Erratum issuedErratum.2020
Authors and funding
11 authors at 2 institutions in 3 countries.
Jakub JankowskiDivision of Nephrology and Center for Immunity, Inflammation and Regenerative Medicine, Department of Medicine, Departments of.
Heather M PerryDivision of Nephrology and Center for Immunity, Inflammation and Regenerative Medicine, Department of Medicine, Departments of.ORCID 0000-0003-0687-5273
Christopher B MedinaPharmacology.
Liping HuangDivision of Nephrology and Center for Immunity, Inflammation and Regenerative Medicine, Department of Medicine, Departments of.
Junlan YaoDivision of Nephrology and Center for Immunity, Inflammation and Regenerative Medicine, Department of Medicine, Departments of.
Amandeep BajwaDivision of Nephrology and Center for Immunity, Inflammation and Regenerative Medicine, Department of Medicine, Departments of.
Ulrike M LorenzMicrobiology, Immunology, and Cancer Biology, and.
Diane L RosinPharmacology.
Kodi S RavichandranMicrobiology, Immunology, and Cancer Biology, and.
Brant E IsaksonMolecular Physiology and Biological Physics.
Mark D OkusaDivision of Nephrology and Center for Immunity, Inflammation and Regenerative Medicine, Department of Medicine, Departments of mdo7y@virginia.edu.
Carter Center · USCardiovascular Research Center · BR
Funding
TRAINING IN THE PHARMACOLOGICAL SCIENCEST32GM007055 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI LYNCH, KEVIN R. · 1985 to 2022
$7.2MSphingolipids in Acute Kidney Injury and Disease ProgressionR01DK085259 · NIDDK · UNIVERSITY OF VIRGINIA · PI OKUSA, MARK DOUGLAS · 2010 to 2023
$5.0MLeukocyte Trafficking in Acute Renal FailureR01DK062324 · NIDDK · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI OKUSA, MARK DOUGLAS · 2003 to 2016
$4.4MKidney Disease and InflammationT32DK072922 · NIDDK · UNIVERSITY OF VIRGINIA · PI OKUSA, MARK DOUGLAS · 2006 to 2020
$2.6MUltrasound for Non-Invasive Prevention of Acute Kidney InjuryR01DK105133 · NIDDK · UNIVERSITY OF VIRGINIA · PI OKUSA, MARK DOUGLAS · 2015 to 2019
$2.4MSphingosine 1 phosphate receptors 1 and 3 as novel targets in transplantationK01DK091444 · NIDDK · UNIVERSITY OF VIRGINIA · PI BAJWA, AMANDEEP · 2012 to 2016
$579kMBF Bioscience and Zeiss Microscope System for Stereology and Tissue MorphologyS10RR026799 · NCRR · UNIVERSITY OF VIRGINIA · PI OKUSA, MARK DOUGLAS · 2010 to 2010
$278kIschemic Reperfusion injury in Transplantation: Role of Sphingosine 1-phosphate receptors and dendritic cellsR03DK107941 · NIDDK · UNIVERSITY OF VIRGINIA · PI BAJWA, AMANDEEP · 2016 to 2017
$158kEndothelial sphingosine-1-phosphate receptor 1 regulates renal recovery after acute kidney injuryF32DK108563 · NIDDK · UNIVERSITY OF VIRGINIA · PI PERRY, HEATHER M. · 2015 to 2017
$115kNCRR NIH HHS S10 RR026799NIDDK NIH HHS F32 DK108563NIDDK NIH HHS K01 DK091444NIDDK NIH HHS R01 DK062324NIDDK NIH HHS R01 DK085259NIDDK NIH HHS R01 DK105133NIDDK NIH HHS R03 DK107941NIDDK NIH HHS T32 DK072922NIGMS NIH HHS T32 GM007055
Abstract
PubMed holds no abstract for this paper.
Indexed as
Acute Kidney InjuryAdenosine TriphosphateAnimalsAnti-Ulcer AgentsBone Marrow CellsCarbenoxoloneConnexinsCytokinesDisease Models, AnimalEndothelial CellsEndothelium, VascularEpithelial CellsIntercellular Adhesion Molecule-1MaleMiceMice, KnockoutAdenosine TriphosphateAnti-Ulcer AgentsCarbenoxoloneConnexinsCytokinesIcam1 protein, mouseIntercellular Adhesion Molecule-1Nerve Tissue ProteinsPanx1 protein, mouseRNA, Messengeracute renal failureATPischemia-reperfusionpurinergic signaling
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.