ArticleBalkan medical journal2018
The Clinicopathologic Spectrum of IgG4-Related Disease
Article in Balkan medical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Article
- IgG4-related retroperitoneal fibrosis: a rare cause of obstructive uropathy.Annals of the Royal College of Surgeons of England · 2022Article
- A rare case of IgG4-related disease masquerading as periurethral malignancy and review of the literature.Frontiers in immunology · 2022Review
- T Cell Roles and Activity in Chronic Sclerosing Sialadenitis as IgG4-Related Disease: Current Concepts in Immunopathogenesis.Autoimmune diseases · 2022Review
- Single Institutional Experience on Orbital Inflammatory Pseudotumor: Diagnostic and Management Challenge.Balkan medical journal · 2021Article
- [IgG4-associated lung disease with granulomatous lesions : Coexistence of two entities or the spectrum of one disease?]Der Pathologe · 2021Article
- Review
- IgG4 sclerosing disease of the esophagus: a case-based review.Rheumatology international · 2020Review
- Inflammatory choroidal neovascularization associated with immunoglobulin G4-related disease: a case report.Journal of medical case reports · 2020Article
- Cutaneous involvement in a case of multifocal idiopathic fibrosclerosis.JAAD case reports · 2020Article
- IgG4-related orbitopathy as an important differential diagnosis of advanced silent sinus syndrome.HNO · 2020Article
- IgG4 Related Kidney Disease with Extra-Renal Involvement Demonstrated on FDG PET/CT.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaArticle
- Pancreatitis, Cholangitis, and Gastritis: The Triumvirate of Immunoglobulin G4-Related Disease Identified Simultaneously onIndian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaArticle
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immunoglobulin G4-related disease is a fibroinflammatory systemic disease that is characterized by focal or diffuse organ infiltration by immunoglobulin G4-bearing plasma cells. Immunoglobulin G4-related disease may affect any organ, and a high index of suspicion is necessary for early detection to avoid irreversible fibrosis, organ dysfunction, and death. Tumor-forming lesions are common radiological features of immunoglobulin G4-related disease that need to be differentiated from malignancies. The diagnostic approach requires the integration of clinical, biochemical, and radiographic manifestations with classic histopathologic features, which remain crucial to diagnosis. The histology of immunoglobulin G4-related disease is determined by a dense lymphoplasmacytic infiltrate, storiform fibrosis, and obliterative phlebitis in the presence of increased immunoglobulin G4-positve plasma cells. Although immunoglobulin G4-related disease forms a distinct, clinically independent disease category, many questions and problems remain unanswered, especially on its pathogenesis and the role of immunoglobulin G4. Advances in the understanding of immunoglobulin G4-related disease are likely to change the diagnostic approach in the future and create potential targets for therapeutic purposes. Here we describe the concept of immunoglobulin G4-related disease and the most recent knowledge in the clinico-pathological characteristics on this emerging disease. This study can guide clinicians in early diagnosis and prevent unnecessary surgical resections.
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