ReviewParasites & vectors2018
Pyrethroid resistance in the dengue vector Aedes aegypti in Southeast Asia: present situation and prospects for management.
Review in Parasites & vectors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
73 citing papers in PubMed, 2 syntheses or guidelines pooled it, 173 citations in OpenAlex.
- A Systematic Review of Mathematical Models of Dengue Transmission and Vector Control: 2010-2020.Viruses · 2023Pooled it
- Insecticide resistance of Dengue vectors in South East Asia: a systematic review.African health sciences · 2021Pooled it
- Synthesis, Structure-Activity Considerations and Histopathological Effects of Diborane Derivatives as Mosquito Larvicides.Acta parasitologica · 2026Article
- Article
- Insecticide susceptibility and knockdown resistance (Kdr) mutations (F1534C and V1016I) in Aedes aegypti populations from Dar es Salaam, Tanzania.Parasites & vectors · 2026Article
- The susceptibility status of Aedes aegypti (Diptera: Culicidae) mosquitoes in Malaysia on pyrethroid and organophosphate insecticides with first detection of T1520I mutation.Scientific reports · 2026Article
- Article
- Rising of pyrethroid resistance mutations (kdr) in the dengue vectorFrontiers in public health · 2026Article
- Global distribution and impact of knockdown resistance mutations in Aedes aegypti on pyrethroid resistance.Parasites & vectors · 2025Review
- Trehalose supports the growth of Aedes aegypti cells and modifies gene expression and dengue virus type 2 replication.PLoS pathogens · 2025Article
- Resistance status ofNarra J · 2025Review
- Consequences of insecticide overuse in Hungary: assessment of pyrethroid resistance in Culex pipiens and Aedes albopictus mosquitoes.Parasites & vectors · 2025Article
- First detection of the S989P+V1016G+D1763Y haplotype and expansion of voltage-gated sodium channel mutations in Aedes aegypti in Taiwan in 2016-2023.PLoS neglected tropical diseases · 2025Article
- Encapsulation of Beauveria bassiana conidia as a new strategy for the biological control of Aedes aegypti larvae.Scientific reports · 2024Article
- A unique mechanism of transfluthrin action revealed by mapping its binding sites in the mosquito sodium channel.Insect biochemistry and molecular biology · 2024Article
- Insecticide Resistance inInsects · 2024Article
- Review of dengue vectors in Cambodia: distribution, bionomics, vector competence, control and insecticide resistance.Parasites & vectors · 2024Review
- Sergentomyia khawi: a potential vector for Leishmania and Trypanosoma parasites affecting humans and animals and insecticide resistance status in endemic areas of Songkhla, southern Thailand.Parasites & vectors · 2024Article
- Upsurge of dengue outbreaks in several WHO regions: Public awareness, vector control activities, and international collaborations are key to prevent spread.Health science reports · 2024Review
- Efficacy of the insect growth regulator novaluron in the control of dengue vector mosquitoes Aedes aegypti and Ae. albopictus.Scientific reports · 2024Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Human arboviral diseases transmitted by Aedes aegypti such as dengue, Zika, chikungunya and yellow fever remain global public health threats to date. Of these diseases, dengue fever is particularly prevalent in Southeast Asia. Relentless vector control efforts are performed to curtail disease transmissions through which pyrethroid insecticides are broadly used as the first line of defense to control Ae. aegypti, especially in the course of disease outbreaks. Here, we compile the largest contemporary database for susceptibility profiles and underlying mechanisms involved in Ae. aegypti resistant to pyrethroids in Southeast Asia. The extensive use of pyrethroids inevitably elicit different levels of resistance to numerous populations despite the presence of geographical isolation. The most common mechanisms of pyrethroid resistance that have been identified in Ae. aegypti includes mutations in the voltage sensitive sodium channel gene (Vssc gene) and metabolic-mediated insecticide resistance. Aedes aegypti develops resistance to pyrethroids by acquisition of one or several amino acid substitution(s) in this Vssc gene. Enzymes involved in metabolic-mediated detoxification (i.e. monooxygenases, glutathione-S-transferases and esterases) have been reported to be related to pyrethroid resistance but many specific contributory enzymes are not completely studied. An inadequate amount of data from some countries indicates an urgent need for further study to fill the knowledge gaps. Perspectives and future research needs are also discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.