ArticleGenome biology2018
A major locus controls local adaptation and adaptive life history variation in a perennial plant.
Article in Genome biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 147 citations in OpenAlex.
- Dissecting the genetic basis of climatic adaptation in wild relatives (Malus baccata) for climate-resilient apple breeding.Journal of integrative plant biology · 2026Article
- A drought stress-induced MYB transcription factor regulates pavement cell shape in leaves of European aspen (Populus tremula).The New phytologist · 2026Article
- Similar Habitat Gradients Across Native and Invasive Ranges Elicit Divergent Evolutionary Responses.Ecology and evolution · 2026Article
- Comparative single-nucleus transcriptomics reveals asymmetric evolution of the Drosophila male and female germlines.PLoS biology · 2026Article
- Natural variation inScience advances · 2026Article
- Natural variants ofScience advances · 2025Article
- Overexpression of Tempranillo-Like Proteins Promotes Dormancy Release in Poplar.Plant, cell & environment · 2025Article
- Elucidating Continental-Wide Phylogeographic and Adaptive Processes Shaping the Genome-Wide Diversity of North America's Most Widely Distributed Tree.Molecular ecology · 2025Article
- Biodiversity Genomics Research Practices Require Harmonising to Meet Stakeholder Needs in Conservation.Molecular ecology · 2025Review
- Dichotomous transcriptome divergence at the cell-type level between thebioRxiv : the preprint server for biology · 2025Article
- Population structure limits the use of genomic data for predicting phenotypes and managing genetic resources in forest trees.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Causes of heterozygosity excess: The case of Mexican populations ofPlant diversity · 2025Article
- Assisted Gene Flow Management to Climate Change in the Annual LegumeEvolutionary applications · 2025Article
- Nature's Master of Ceremony: TheNpj biological timing and sleep · 2025Article
- Transcriptome differentiation in Cryptomeria japonica trees with different origins growing in the north and south of Japan.PloS one · 2025Article
- Multi-omics analysis reveals genetic architecture and local adaptation of coumarins metabolites in Populus.BMC plant biology · 2024Article
- Integrating evolutionary genomics of forest trees to inform future tree breeding amid rapid climate change.Plant communications · 2024Review
- Genomic variation of European beech reveals signals of local adaptation despite high levels of phenotypic plasticity.Nature communications · 2024Article
- The genetic architecture of repeated local adaptation to climate in distantly related plants.Nature ecology & evolution · 2024Article
- Why we thrive beneath a northern sky - genomic signals of selection in apple for adaptation to northern Sweden.Heredity · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe initiation of growth cessation and dormancy represent critical life-history trade-offs between survival and growth and have important fitness effects in perennial plants. Such adaptive life-history traits often show strong local adaptation along environmental gradients but, despite their importance, the genetic architecture of these traits remains poorly understood.
resultsWe integrate whole genome re-sequencing with environmental and phenotypic data from common garden experiments to investigate the genomic basis of local adaptation across a latitudinal gradient in European aspen (Populus tremula). A single genomic region containing the PtFT2 gene mediates local adaptation in the timing of bud set and explains 65% of the observed genetic variation in bud set. This locus is the likely target of a recent selective sweep that originated right before or during colonization of northern Scandinavia following the last glaciation. Field and greenhouse experiments confirm that variation in PtFT2 gene expression affects the phenotypic variation in bud set that we observe in wild natural populations.
conclusionsOur results reveal a major effect locus that determines the timing of bud set and that has facilitated rapid adaptation to shorter growing seasons and colder climates in European aspen. The discovery of a single locus explaining a substantial fraction of the variation in a key life-history trait is remarkable, given that such traits are generally considered to be highly polygenic. These findings provide a dramatic illustration of how loci of large-effect for adaptive traits can arise and be maintained over large geographical scales in natural populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.