ArticleBMC ophthalmology2018
Association between blood pressure and retinal arteriolar and venular diameters in Chinese early adolescent children, and whether the association has gender difference: a cross-sectional study.
Article in BMC ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Association of Retinal Arterial Narrowing With New-Onset Carotid Plaque: A Chinese Community-Based Nested Case-Control Cohort Study.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Optic disc and retinal vascular features in first 6 years of Chinese children.Frontiers in pediatrics · 2023Article
- Automated Systems for Calculating Arteriovenous Ratio in Retinographies: A Scoping Review.Diagnostics (Basel, Switzerland) · 2022Article
- Serum and Macular Carotenoids in Relation to Retinal Vessel Caliber Fifteen Years Later, in the Second Carotenoids in Age-Related Eye Disease Study.Investigative ophthalmology & visual science · 2021Article
- Relationship between Retinal Microvasculature, Cardiovascular Risk and Silent Brain Infarction in Hypertensive Patients.Diagnostics (Basel, Switzerland) · 2021Article
- Diagnosis of chronic stage of hypertensive retinopathy based on spectral domain optical coherence tomography.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- Influencing factors for peripheral and posterior lesions in mild non-proliferative diabetic retinopathy-the Kailuan Eye Study.International journal of ophthalmology · 2020Article
- Short- and Long-Term Effects of Bariatric Surgery on Vascular Phenotype.Obesity surgery · 2019Observational
- Intravitreal bevacizumab versus ranibizumab: Effects on the vessels of the fellow non-treated eye.Journal of current ophthalmology · 2019Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo establish the independent association between blood pressure (BP) and retinal vascular caliber, especially the retinal venular caliber, in a population of 12-year-old Chinese children.
methodsWe have examined 1501 students in the 7th grade with mean age of 12.7 years. A non-mydriatic fundus camera (Canon CR-2, Tokyo, Japan) was used to capture 45
resultsThe mean retinal arteriolar caliber was 145.3 μm (95% confidence interval [CI], 110.6-189.6 μm) and the mean venular caliber was 212.7 μm (95% CI, 170.6-271.3 μm). After controlling for age, sex, axial length, BMI, waist, spherical equivalent, birth weight, gestational age and fellow retinal vessel caliber, children in the highest quartile of BP had significantly narrower retinal arteriolar caliber than those with lower quartiles (P for trend< 0.05). Each 10-mmHg increase in BP was associated with narrowing of the retinal arterioles by 3.00 μm (multivariable-adjusted P < 0.001), and the results were consist in three BP measurements. The association between BP measures and retinal venular caliber did not persist after adjusting for fellow arteriolar caliber. And there was no significant interaction between BP and sex, age, BMI, and birth status.
conclusionsIn a large population of adolescent Chinese children, higher BP was found to be associated with narrower retinal arterioles, but not with retinal venules. Sex and other confounding factors had no effect on the relationship of BP and retinal vessel diameter.
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