Evidence map›Paper›PMID 29865278›Full record

ReviewMaterials (Basel, Switzerland)2018

Secondary Metabolites in the Green Synthesis of Metallic Nanoparticles.

Gregory Marslin, Karthik Siram, Qaisar Maqbool, Rajendran Kamalabai Selvakesavan, Dariusz Kruszka, Piotr Kachlicki, Gregory Franklin

RetractedErratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 130 papers.

0numbers the graph read from it
0cells of the map it votes in
130citing papers in PubMed
15.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

130 citing papers in PubMed, 516 citations in OpenAlex.

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  6. Food science & nutrition · 2026
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70 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Gregory MarslinRatnam Institute of Pharmacy and Research, Nellore 524346, India. marslingregory@gmail.com.ORCID 0000-0002-2383-2382
Karthik SiramDepartment of Pharmaceutics, PSG College of Pharmacy, Coimbatore 641004, India. karthiksiram@gmail.com.
Qaisar MaqboolInstitute of Plant Genetics of the Polish Academy of Sciences, Poznan 60479, Poland. Qaisar.vu@gmail.com.ORCID 0000-0002-5882-2117
Rajendran Kamalabai SelvakesavanInstitute of Plant Genetics of the Polish Academy of Sciences, Poznan 60479, Poland. kesavanrks@gmail.com.
Dariusz KruszkaInstitute of Plant Genetics of the Polish Academy of Sciences, Poznan 60479, Poland. dmkruszka@gmail.com.
Piotr KachlickiInstitute of Plant Genetics of the Polish Academy of Sciences, Poznan 60479, Poland. pkac@igr.poznan.pl.ORCID 0000-0003-3777-8273
Gregory FranklinInstitute of Plant Genetics of the Polish Academy of Sciences, Poznan 60479, Poland. fgre@igr.poznan.pl.ORCID 0000-0002-6745-3528
Institute of Plant Genetics, Polish Academy of Sciences · PLPSG INSTITUTE OF TECHNOLOGY AND APPLIED RESEARCH · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability of organisms and organic compounds to reduce metal ions and stabilize them into nanoparticles (NPs) forms the basis of green synthesis. To date, synthesis of NPs from various metal ions using a diverse array of plant extracts has been reported. However, a clear understanding of the mechanism of green synthesis of NPs is lacking. Although most studies have neglected to analyze the green-synthesized NPs (GNPs) for the presence of compounds derived from the extract, several studies have demonstrated the conjugation of sugars, secondary metabolites, and proteins in these biogenic NPs. Despite several reports on the bioactivities (antimicrobial, antioxidant, cytotoxic, catalytic, etc.) of GNPs, only a handful of studies have compared these activities with their chemically synthesized counterparts. These comparisons have demonstrated that GNPs possess better bioactivities than NPs synthesized by other methods, which might be attributed to the presence of plant-derived compounds in these NPs. The ability of NPs to bind with organic compounds to form a stable complex has huge potential in the harvesting of precious molecules and for drug discovery, if harnessed meticulously. A thorough understanding of the mechanisms of green synthesis and high-throughput screening of stabilizing/capping agents on the physico-chemical properties of GNPs is warranted to realize the full potential of green nanotechnology.

Indexed as

bioactivitiesdrug discoveryflavonoidsgreen synthesisnano-harvestingnanoparticlessecondary metabolites

Identifiers

PMID29865278
PMCPMC6024997
OpenAlexW2805109650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.