Evidence map›Paper›PMID 29865277›Full record

ReviewNanomaterials (Basel, Switzerland)2018

Magnetic Hyperthermia and Radiation Therapy: Radiobiological Principles and Current Practice

Spiridon V Spirou, Martina Basini, Alessandro Lascialfari, Claudio Sangregorio, Claudia Innocenti

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Spatiotemporal cancer controlNanomedicine (London, England) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Spiridon V SpirouDepartment of Radiology, Sismanoglio General Hospital of Attica, Sismanogliou 1, Marousi 15126, Greece. spiridonspirou@yahoo.com.ORCID 0000-0003-3487-389X
Martina BasiniUniversità degli Studi di Milano, Dipartimento di Fisica, Via Celoria 16, 20133 Milano, Italy. martina.basini@gmail.com.
Alessandro LascialfariUniversità degli Studi di Milano, Dipartimento di Fisica, Via Celoria 16, 20133 Milano, Italy. alessandro.lascialfari@unimi.it.
Claudio SangregorioICCOM-CNR via Madonna del Piano 10, 50019 Sesto Fiorentino, Italy. csangregorio@iccom.cnr.it.ORCID 0000-0002-2655-3901
Claudia InnocentiICCOM-CNR via Madonna del Piano 10, 50019 Sesto Fiorentino, Italy. claudia.innocenti@unifi.it.ORCID 0000-0003-3705-4283

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperthermia, though by itself generally non-curative for cancer, can significantly increase the efficacy of radiation therapy, as demonstrated by in vitro, in vivo, and clinical results. Its limited use in the clinic is mainly due to various practical implementation difficulties, the most important being how to adequately heat the tumor, especially deep-seated ones. In this work, we first review the effects of hyperthermia on tissue, the limitations of radiation therapy and the radiobiological rationale for combining the two treatment modalities. Subsequently, we review the theory and evidence for magnetic hyperthermia that is based on magnetic nanoparticles, its advantages compared with other methods of hyperthermia, and how it can be used to overcome the problems associated with traditional techniques of hyperthermia.

Indexed as

cancer therapyhyperthermiamagnetic fluid hyperthermiamagnetic nanoparticlesnanomedicineradiation therapy

Identifiers

PMID29865277
PMCPMC6027353

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.