Evidence map›Paper›PMID 29865233›Full record

ReviewInternational journal of molecular sciences2018

Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting.

Maria Elisabeth Street, Sabrina Angelini, Sergio Bernasconi, Ernesto Burgio, Alessandra Cassio, Cecilia Catellani, Francesca Cirillo, Annalisa Deodati, Enrica Fabbrizi, Vassilios Fanos and 14 more

3 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 94 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 4 pooled it
14.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04679168 unknown statusnot on this mapstarted 2020, after this paper: background citation

Change of Environmental Chemical Exposures and Prevalence of Chronic Kidney Disease After Epidemiological Spread of SARS-CoV-2 (COVID-19)

Typeobservational_patient_registrySponsorSeoul National University HospitalRan2020 to 2021Enrolled310ConditionsCovid19, Environmental Exposure, Chronic Kidney Diseases
NCT05780047 nacompletednot on this mapstarted 2022, after this paper: background citation

Personalized Mobile Intervention to Reduce Exposure to Endocrine Disrupting Chemicals (EDCs) in Women of Child-Bearing Age and Their Partners

TypeinterventionalSponsorMillion Marker Wellness, Inc.Ran2022 to 2022Enrolled434ConditionsEndocrine Disrupting Chemicals, Environmental Exposure, Health Literacy, Bisphenol AArmsMail-in Urine Test for EDCs
NCT07560579 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Weight Loss and Endocrine Disrupting Chemicals (EDCs): Lifestyle Interventions to Lose Weight and Reduce EDC Exposure in Individuals With Overweight/Obesity

TypeinterventionalSponsorMillion Marker Wellness, Inc.Ran2025 to 2026Enrolled226ConditionsObesity &Amp, Amp, Amp, OverweightArmsEducational curriculum, Weight loss Application, Urinary EDC metabolite testing, Siphox clinic biomarker test, Weight loss reporting
3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 4 syntheses or guidelines pooled it, 249 citations in OpenAlex.

  1. Pooled it
  2. Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Review
  7. Article
  8. Review
  9. Endocrine Disruption and Male Fertility.Current environmental health reports · 2026
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Knowledge and attitudes of pregnant women about endocrine disruptors.Revista da Associacao Medica Brasileira (1992) · 2025
    Article
  20. Endocrine disruptors and children's health.Turkish journal of medical sciences · 2025
    Review

34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 11 institutions in 1 country.

Maria Elisabeth StreetDepartment of Obstetrics, Gynaecology and Paediatrics, Azienda USL-IRCCS, Viale Risorgimento 80, 42123 Reggio Emilia, Italy. mariaelisabeth.street@ausl.re.it.ORCID 0000-0001-8427-8971
Sabrina AngeliniDepartment of Pharmacy and Biotechnology, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy. s.angelini@unibo.it.ORCID 0000-0002-1609-0421
Sergio BernasconiFormer Department of Medicine, University of Parma, Via A. Catalani 10, 43123 Parma, Italy. sbernasconi@gmail.com.
Ernesto BurgioECERI European Cancer and Environment Research Institute, Square de Meeus, 38-40, 1000 Bruxelles, Belgium. erburg@libero.it.
Alessandra CassioPediatric Endocrinology Programme, Pediatrics Unit, Department of Woman, Child Health and Urologic Diseases, AOU S. Orsola-Malpighi, Via Massarenti, 11, 40138 Bologna, Italy. alessandra.cassio@unibo.it.
Cecilia CatellaniDepartment of Obstetrics, Gynaecology and Paediatrics, Azienda USL-IRCCS, Viale Risorgimento 80, 42123 Reggio Emilia, Italy. cecilia.catellani@ausl.re.it.ORCID 0000-0002-6354-9979
Francesca CirilloDepartment of Obstetrics, Gynaecology and Paediatrics, Azienda USL-IRCCS, Viale Risorgimento 80, 42123 Reggio Emilia, Italy. francesca.cirillo@ausl.re.it.
Annalisa DeodatiDepartment of Pediatrics (DPUO), Bambino Gesù Children's Hospital, Tor Vergata University, Piazza S. Onofrio 4, 00165 Rome, Italy. annalisa.deodati@opbg.net.
Enrica FabbriziDepartment of Pediatrics and Neonatology, Augusto Murri Hospital, Via Augusto Murri, 17, 63900 Fermo, Itlay. enrica.fabbrizi@libero.it.
Vassilios FanosNeonatal Intensive Care Unit, Neonatal Pathology and Neonatal Section, AOU and University of Cagliari, via Ospedale, 54, 09124 Cagliari, Italy. vafanos@tiscali.it.
Giancarlo GarganoDepartment of Obstetrics, Gynaecology and Paediatrics, Azienda USL-IRCCS, Viale Risorgimento 80, 42123 Reggio Emilia, Italy. giancarlo.gargano@ausl.re.it.ORCID 0000-0001-5602-0316
Enzo GrossiVilla Santa Maria Institute, Neuropsychiatric Rehabilitation Center, Via IV Novembre 15, 22038 Tavernerio (Como), Italy. enzo.grossi@bracco.com.
Lorenzo IughettiDepartment of Medical and Surgical Sciences of the Mother, Children and Adults, Pediatrics Unit, University of Modena and Reggio Emilia, via del Pozzo, 71, 41124 Modena, Italy. lorenzo.iughetti@unimore.it.ORCID 0000-0003-0370-7872
Pietro LazzeroniDepartment of Obstetrics, Gynaecology and Paediatrics, Azienda USL-IRCCS, Viale Risorgimento 80, 42123 Reggio Emilia, Italy. pietro.lazzeroni@ausl.re.it.
Alberto MantovaniDepartment of Veterinary Public Health and Food Safety, Food and Veterinary Toxicology Unit ISS⁻National Institute of Health, Viale Regina Elena 299, 00161 Rome, Italy. alberto.mantovani@iss.it.
Lucia MiglioreDepartment of Traslational Research and New Technologies in Medicine and Surgery, University of Pisa, Via Roma, 55, 56123 Pisa, Italy. lucia.migliore@med.unipi.it.
Paola PalanzaUnit of Neuroscience, Department of Medicine and Surgery, University of Parma, Via Gramsci, 14, 43126 Parma, Italy. paola.palanza@unipr.it.ORCID 0000-0003-2873-4260
Giancarlo PanzicaLaboratory of Neuroendocrinology, Department of Neuroscience Rita Levi Montalcini, University of Turin, Via Cherasco 15, 10126 Turin, Italy. giancarlo.panzica@unito.it.ORCID 0000-0002-9302-4647
Anna Maria PapiniDepartment of Chemistry 'Ugo Schiff', University of Florence, Via della Lastruccia, 3-13, 50019 Sesto Fiorentino, Florence, Italy. annamaria.papini@unifi.it.ORCID 0000-0002-2947-7107
Stefano ParmigianiUnit of Evolutionary and Functional Biology-Department of Chemistry, Life Sciences and Environmental Sustainability (SCVSA)-University of Parma⁻11/a, 43124 Parma, Italy. stefano.parmigiani@unipr.it.
Barbara PredieriDepartment of Medical and Surgical Sciences of the Mother, Children and Adults, Pediatrics Unit, University of Modena and Reggio Emilia, via del Pozzo, 71, 41124 Modena, Italy. barbara.predieri@unimore.it.ORCID 0000-0002-3302-6886
Chiara SartoriDepartment of Obstetrics, Gynaecology and Paediatrics, Azienda USL-IRCCS, Viale Risorgimento 80, 42123 Reggio Emilia, Italy. chiara.sartori@ausl.re.it.
Gabriele TridentiDepartment of Obstetrics, Gynaecology and Paediatrics, Azienda USL-IRCCS, Viale Risorgimento 80, 42123 Reggio Emilia, Italy. gabriele.tridenti@ausl.re.it.
Sergio AmarriDepartment of Obstetrics, Gynaecology and Paediatrics, Azienda USL-IRCCS, Viale Risorgimento 80, 42123 Reggio Emilia, Italy. sergio.amarri@ausl.re.it.
Istituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Parma · ITUniversity of Modena and Reggio Emilia · ITBambino Gesù Children's Hospital · ITIRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITIstituto Superiore di Sanità · ITNeuroscience Institute · ITUniversity of Bologna · ITUniversity of Cagliari · ITUniversity of Florence · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wildlife has often presented and suggested the effects of endocrine disrupting chemicals (EDCs). Animal studies have given us an important opportunity to understand the mechanisms of action of many chemicals on the endocrine system and on neurodevelopment and behaviour, and to evaluate the effects of doses, time and duration of exposure. Although results are sometimes conflicting because of confounding factors, epidemiological studies in humans suggest effects of EDCs on prenatal growth, thyroid function, glucose metabolism and obesity, puberty, fertility, and on carcinogenesis mainly through epigenetic mechanisms. This manuscript reviews the reports of a multidisciplinary national meeting on this topic.

Indexed as

AnimalsCarcinogenesisEndocrine DisruptorsEndocrine SystemEpigenesis, GeneticFemaleGlucoseHumansObesityPregnancyEndocrine DisruptorsGlucoseautismcarcinogenesisEndocrine Disrupting Chemicals (EDCs)epigeneticsfertilitygrowthneurodevelopmentobesitypubertythyroid function

Identifiers

PMID29865233
PMCPMC6032228
OpenAlexW2807662106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.