Evidence map›Paper›PMID 29865203›Full record

ArticleInternational journal of molecular sciences2018

LAT1-Targeting Thermoresponsive Fluorescent Polymer Probes for Cancer Cell Imaging.

Minami Matsuura, Mariko Ohshima, Yuki Hiruta, Tomohiro Nishimura, Kenichi Nagase, Hideko Kanazawa

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Temperature-modulated separation of therapeutic cells, viral vectors, and exosomes using functional polymers.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Bioanalytical technologies using temperature-responsive polymers.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Effective Separation for New Therapeutic Modalities Utilizing Temperature-responsive Chromatography.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2021
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Minami MatsuuraFaculty of Pharmacy, Keio University, 1-5-30, Shibakoen, Minato-ku, Tokyo 105-8012, Japan. Minami_Matsuura@terumo.co.jp.
Mariko OhshimaFaculty of Pharmacy, Keio University, 1-5-30, Shibakoen, Minato-ku, Tokyo 105-8012, Japan. marikoda113@keio.jp.
Yuki HirutaDepartment of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan. hiruta@applc.keio.ac.jp.
Tomohiro NishimuraFaculty of Pharmacy, Keio University, 1-5-30, Shibakoen, Minato-ku, Tokyo 105-8012, Japan. nishimura-tm@pha.keio.ac.jp.
Kenichi NagaseFaculty of Pharmacy, Keio University, 1-5-30, Shibakoen, Minato-ku, Tokyo 105-8012, Japan. nagase-kn@pha.keio.ac.jp.ORCID 0000-0002-6575-0107
Hideko KanazawaFaculty of Pharmacy, Keio University, 1-5-30, Shibakoen, Minato-ku, Tokyo 105-8012, Japan. kanazawa-hd@pha.keio.ac.jp.ORCID 0000-0003-2550-470X
Keio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

L-type amino acid transporter 1 (LAT1) is more highly expressed in cancer cells compared with normal cells. LAT1 targeting probes would therefore be a promising tool for cancer cell imaging. In this study, LAT1-targeting thermoresponsive fluorescent polymer probes based on poly(

Indexed as

AcrylamidesFluorescent DyesHeLa CellsHot TemperatureHumansHydrophobic and Hydrophilic InteractionsLarge Neutral Amino Acid-Transporter 1LeucineMolecular ImagingNeoplasmsPolymersAcrylamidesFluorescent DyesLarge Neutral Amino Acid-Transporter 1LeucineN-isopropylacrylamideN,N-dimethylacrylamidePolymersfluorescent polymer probeL-type amino acid transporter 1 targetingpoly(N-isopropylacrylamide)

Identifiers

PMID29865203
PMCPMC6032285
OpenAlexW2805220003

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.