Evidence map›Paper›PMID 29865187›Full record

ArticleInternational journal of molecular sciences2018

Butterbur Leaves Attenuate Memory Impairment and Neuronal Cell Damage in Amyloid Beta-Induced Alzheimer's Disease Models.

Namkwon Kim, Jin Gyu Choi, Sangsu Park, Jong Kil Lee, Myung Sook Oh

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. International journal of molecular sciences · 2026
    Article
  2. Anti-Photoaging Effects of a Standardized Hot Water Extract ofPharmaceuticals (Basel, Switzerland) · 2025
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  5. Aqueous extract ofNutrition research and practice · 2021
    Article
  6. Article
  7. Article
  8. Antioxidant compounds ofJournal of clinical biochemistry and nutrition · 2020
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Namkwon KimDepartment of Life and Nanopharmaceutical Sciences, Graduate School, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea. kop03@khu.ac.kr.
Jin Gyu ChoiBK21 PLUS Integrated Education and Research Center for Nature-Inspired Drug Development Targeting Healthy Aging, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea. choijg2002@khu.ac.kr.
Sangsu ParkNATUREBIO Co., Ltd., 132, Pureunsol Culture Hall, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea. x-zara@nate.com.
Jong Kil LeeDepartment of Pharmacy, College of Pharmacy, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea. jklee3984@khu.ac.kr.
Myung Sook OhDepartment of Life and Nanopharmaceutical Sciences, Graduate School, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea. msohok@khu.ac.kr.
Kyung Hee University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease, and is characterized by the accumulation of amyloid beta (Aβ) as a pathological hallmark. Aβ plays a central role in neuronal degeneration and synaptic dysfunction through the generation of excessive oxidative stress. In the present study, we explored whether leaves of

Indexed as

Disease Models, AnimalAlzheimer DiseaseAmyloid beta-PeptidesAnimalsApoptosisCells, CulturedMaleMemory DisordersMiceNeuronsNeuroprotective AgentsOxidative StressPeptide FragmentsPetasitesPlant ExtractsPlant LeavesAmyloid beta-Peptidesamyloid beta-protein (25-35)Neuroprotective AgentsPeptide FragmentsPlant ExtractsAlzheimer’s diseaseamyloid betabutterburmemoryPetasites japonicus

Identifiers

PMID29865187
PMCPMC6032106
OpenAlexW2806378162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.