SynthesisPloS one2018
Language outcome related to brain structures in school-aged preterm children: A systematic review.
Synthesis in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Effects of prematurity and socio-economic status on early life language exposure: A video coding study.The British journal of developmental psychology · 2026Article
- Neural and behavioural correlates of theory of mind reasoning in five-year-old children born preterm.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Article
- Neuroimaging in pediatric language development and disorders: a scoping review protocol.Systematic reviews · 2025Article
- Does the Maternal Gut Microbiome Influence the Outcome of Perinatal Asphyxia?Antioxidants (Basel, Switzerland) · 2025Review
- Lateralization of Neural Speech Discrimination at Birth Is a Predictor for Later Language Development.Developmental science · 2025Article
- Cerebellar Development and the Burden of Prematurity.Cerebellum (London, England) · 2025Review
- Listening to mom in the neonatal intensive care unit: a randomized trial of increased maternal speech exposure on white matter connectivity in infants born preterm.Frontiers in human neuroscience · 2025Article
- Interactive roles of preterm-birth and socioeconomic status in cortical thickness of language-related brain structures: Findings from the Adolescent Brain Cognitive Development (ABCD) study.Cortex; a journal devoted to the study of the nervous system and behavior · 2024Article
- Language performance and brain volumes, asymmetry, and cortical thickness in children born extremely preterm.Pediatric research · 2024Article
- Corpus Callosum Abnormalities at Term-Equivalent Age Are Associated with Language Development at 2 Years' Corrected Age in Infants Born Very Preterm.Journal of pediatrics. Clinical practice · 2024Article
- Impact of COVID-19 pandemic on neurodevelopmental outcome in very low birth weight infants: a nationwide cohort study.Frontiers in pediatrics · 2024Article
- The frequency-following response in late preterm neonates: a pilot study.Frontiers in psychology · 2024Article
- Corpus callosum abnormalities at term-equivalent age are associated with language development at two years corrected age in infants born very preterm.medRxiv : the preprint server for health sciences · 2023Article
- Preterm birth and neonatal white matter microstructure in in-vivo reconstructed fiber tracts among audiovisual integration brain regions.Developmental cognitive neuroscience · 2023Article
- Extreme prematurity and perinatal risk factors related to extremely preterm birth are associated with complex patterns of regional brain volume alterations at 10 years of age: a voxel-based morphometry study.Frontiers in neurology · 2023Article
- Microstructural alterations in association tracts and language abilities in schoolchildren born very preterm and with poor fetal growth.Pediatric radiology · 2023Article
- Chronic pediatric diseases and risk for reading difficulties: a narrative review with recommendations.Pediatric research · 2022Review
- Cerebellar volumes and language functions in school-aged children born very preterm.Pediatric research · 2021Article
- Microstructural Measures of the Inferior Longitudinal Fasciculus Predict Later Cognitive and Language Development in Infants Born With Extremely Low Birth Weight.Journal of child neurology · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Preterm children often have language problems. This atypical language development is probably due to atypical brain development. We conducted a systematic review to provide an overview of the extensive and diverse scientific literature on the relations between language outcome and underlying brain structures in school-aged preterm-born children. Embase, Medline Ovid, Web of Science, Cochrane central and Google scholar were searched for relevant studies. Inclusion criteria were: cases are school-aged preterm children; structural MRI (T1- and T2-weighted sequences) or DTI used in combination with a neurocognitive language test; publication in an English-language peer-reviewed journal. Correlational measures between language scores and brain volume or fractional anisotropy of a brain structure were extracted. 23 studies were included. The relations between oral language, verbal fluency and/or written language and MRI/DTI measurements of white matter, gray matter, cerebellum, corpus callosum and/or the fasciculi are presented. Oral language skills and verbal fluency appear to be related to the corpus callosum. Oral language skills are also related to the uncinate fasciculus. There seems to be no clear relation between cerebellar development and verbal fluency skills. Not one single brain area is responsible for atypical language development, but several brain areas and their connections are essential. For future research it is recommended to relate brain areas to oral language skills on a microstructural level in preterm children. We also recommend to use language tests in which it is possible to distinguish between several language domains, such as perceptive and expressive language.
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