ArticleEnvironmental health perspectives2018
Exposures Related to House Dust Microbiota in a U.S. Farming Population.
Article in Environmental health perspectives, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Trial
- Residential proximity to intensive animal agriculture associates with increased prevalence of antimicrobial resistance in homes.Journal of exposure science & environmental epidemiology · 2026Article
- Household environmental characteristics influence the house dust metagenome.Environmental research · 2026Article
- Microbial landscape of Indian homes: the microbial diversity, pathogens and antimicrobial resistome in urban residential spaces.Environmental microbiome · 2025Article
- Article
- Pesticide use and inflammatory bowel disease in licensed pesticide applicators and spouses in the Agricultural Health Study.Environmental research · 2024Article
- Occupational farm work activities influence workers' indoor home microbiome.Environmental research · 2024Article
- Enrichment of human nasopharyngeal bacteriome with bacteria from dust after short-term exposure to indoor environment: a pilot study.BMC microbiology · 2023Article
- Metagenomics reveals novel microbial signatures of farm exposures in house dust.medRxiv : the preprint server for health sciences · 2023Article
- Metagenomics reveals novel microbial signatures of farm exposures in house dust.Frontiers in microbiology · 2023Article
- Indoor endotoxin, proximity to a major roadway, and severe asthma exacerbations among children in Puerto Rico.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2020Article
- Recent Research on Occupational Animal Exposures and Health Risks: A Narrative Review.Current environmental health reports · 2019Review
- Archaea and Bacteria Exposure in Danish Livestock Farmers.Annals of work exposures and health · 2019Article
- How a farming environment protects from atopy.Current opinion in immunology · 2019Review
- Endotoxin andEnvironmental health perspectives · 2019Article
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Authors and funding
10 authors.
Funding
Abstract
backgroundEnvironmental factors can influence the house dust microbiota, which may impact health outcomes. Little is known about how farming exposures impact the indoor microbiota.
objectiveWe aimed to identify exposures related to bacterial communities in house dust in a U.S. farming population.
methodsWe used 16S rRNA amplicon sequencing to characterize bacterial communities in vacuumed dust samples from the bedrooms of a subset of 879 households of farmers and farmers' spouses enrolled in the Agricultural Lung Health Study (ALHS), a case-control study of asthma nested within the Agricultural Health Study (AHS) in North Carolina and Iowa. Information on current farming (past 12 mo), including both crop and animal farming, and other potential microbial sources was obtained via questionnaires. We used linear regression to evaluate associations between exposures and bacterial diversity within each sample, analysis of similarity (ANOSIM), and permutational multivariate analysis of variance (PERMANOVA) to identify exposures related to diversity between samples, and analysis of composition of microbiome to examine whether exposures related to diversity were also related to differential abundance of specific operational taxonomic units (OTUs).
resultsCurrent farming was positively associated with bacterial diversity in house dust, with or without adjustment for nonfarm exposures related to diversity, including presence of indoor pets, home condition, and season of dust collection. Many taxa exhibited differential abundance related to farming. Some taxa in the phyla Chloroflexi and Verrucomicrobia were associated [false discovery rate (FDR)<0.05] with farming but not with other nonfarm factors. Many taxa correlated with the concentration of house dust of endotoxin, commonly studied as a general marker of exposure to the farming environment.
conclusionsIn this farming population, house dust microbiota differed by current farming status. Understanding the determinants of the indoor microbiota is the first step toward understanding potential relationships with health outcomes. https://doi.org/10.1289/EHP3145.
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