Evidence map›Paper›PMID 29863657›Full record

ArticleJournal of visualized experiments : JoVE2018

Target Cell Pre-enrichment and Whole Genome Amplification for Single Cell Downstream Characterization.

Shukun Chen, Amin El-Heliebi, Julia Schmid, Karl Kashofer, Zbigniew T Czyż, Bernhard Michael Polzer, Klaus Pantel, Thomas Kroneis, Peter Sedlmayr

Open access · greenAbstract readVideo-Audio Media
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of visualized experiments : JoVE, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 4 countries.

Shukun ChenInstitute of Cell Biology, Histology and Embryology, Medical University of Graz.
Amin El-HeliebiInstitute of Cell Biology, Histology and Embryology, Medical University of Graz.
Julia SchmidInstitute of Cell Biology, Histology and Embryology, Medical University of Graz.
Karl KashoferInstitute of Pathology, Medical University of Graz.
Zbigniew T CzyżFraunhofer Institute for Toxicology and Experimental Medicine ITEM.
Bernhard Michael PolzerFraunhofer Institute for Toxicology and Experimental Medicine ITEM.
Klaus PantelDepartment of Tumor Biology, University Medical Center Hamburg-Eppendorf.
Thomas KroneisInstitute of Cell Biology, Histology and Embryology, Medical University of Graz; Sahlgrenska Cancer Center, University of Gothenburg; thomas.kroneis@medunigraz.at.
Peter SedlmayrInstitute of Cell Biology, Histology and Embryology, Medical University of Graz.
Medical University of Graz · ATFraunhofer Institute for Toxicology and Experimental Medicine · DEUniversität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rare target cells can be isolated from a high background of non-target cells using antibodies specific for surface proteins of target cells. A recently developed method uses a medical wire functionalized with anti-epithelial cell adhesion molecule (EpCAM) antibodies for in vivo isolation of circulating tumor cells (CTCs)

Indexed as

GenomeHumansNucleic Acid Amplification TechniquesSingle-Cell Analysis

Identifiers

PMID29863657
PMCPMC6101176
OpenAlexW2803996010

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.