ReviewAnnals of gastroenterological surgery2018
Mediastinal lymphadenectomy for esophageal cancer: Differences between two countries, Japan and the Netherlands.
Review in Annals of gastroenterological surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Induction Radiochemotherapy for Esophageal Cancer: Long-Term Outcomes from a Single-Center Study.Journal of clinical medicine · 2025Article
- Essential updates 2022/2023: Recent advances in perioperative management of esophagectomy to improve operative outcomes.Annals of gastroenterological surgery · 2024Review
- History and evidence for state of the art of lymphadenectomy in esophageal cancer surgery.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024Review
- Nationwide Association of Surgical Performance of Minimally Invasive Esophagectomy With Patient Outcomes.JAMA network open · 2024Article
- Quality of oncological resection criteria in minimally invasive esophagectomy.Surgical endoscopy · 2022Article
- Efficacy of intraoperative recurrent laryngeal neuromonitoring during surgery for esophageal cancer.Annals of gastroenterological surgery · 2021Article
- Ways and tradition of Japan in esophageal surgery for cancer.General thoracic and cardiovascular surgery · 2020Article
- Impact of the interval between neoadjuvant concurrent chemoradiotherapy and esophagectomy in the modern era: a population-based propensity-score-matched retrospective cohort study in Asia.World journal of surgical oncology · 2019Article
- Minimally invasive mesoesophageal resection.Journal of thoracic disease · 2019Review
- Mediastinal lymphadenectomy for esophageal cancer: Differences between two countries, Japan and the Netherlands.Annals of gastroenterological surgery · 2018Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extent of mediastinal lymphadenectomy during esophagectomy is clearly different between two representative countries of the Eastern and Western world, such as Japan and the Netherlands. In Japan, a clear policy is the standard complete two- or three-field type of lymphadenectomy whereas, in the Netherlands, a limited form is usually carried out. Reasons for these differences can be found in the different types of tumor, 80% of adenocarcinomas in the West and almost 95% of squamous cell cancer in Japan. Moreover, location of the tumors, distally located in the Netherlands whereas, in Japan, the majority are located in the middle and proximal thoracic esophagus. Also, type of neoadjuvant therapy, namely chemoradiotherapy in the Netherlands, and chemotherapy in Japan, are different. Arguments for more extended mediastinal lymphadenectomy are currently challenged in the West, first by the systematic use of chemoradiotherapy as neoadjuvant therapy and, second, the retrospective analysis of large data. According to two studies, the importance of extended lymphadenectomy is shown to be relative and less clear, especially in esophageal adenocarcinomas after neoadjuvant therapy. International efforts such as the TIGER study will help to standardize and find a relationship between the type and location of esophageal cancer, use of neoadjuvant therapy, extent of lymphadenectomy and survival.
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