ReviewAnnals of gastroenterological surgery2017
Does postoperative morbidity worsen the oncological outcome after radical surgery for gastrointestinal cancers? A systematic review of the literature.
Review in Annals of gastroenterological surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
82 citing papers in PubMed, 1 synthesis or guideline pooled it, 126 citations in OpenAlex.
- Robotic gastrectomy for gastric cancer: systematic review and future directions.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2023Pooled it
- Prognostic Impact of Post-operative Infectious Complications in Gastric Cancer Patients Receiving Neoadjuvant Chemotherapy: Post Hoc Analysis of a Randomized Controlled Trial, JCOG0501.Journal of gastrointestinal cancer · 2024Trial
- Preoperative prealbumin levels are prognostic predictors of overall survival, independent of inflammation severity, in patients with gastric cancer following gastrectomy.Surgery today · 2026Article
- ASO Author Reflections: Walking on Thin Statistical Ice: Why Prehabilitation Evidence in Cancer Surgery May Be More Fragile Than We Think.Annals of surgical oncology · 2026Article
- General Principles of Risk Mitigation before Colorectal Surgery.Clinics in colon and rectal surgery · 2026Review
- Preoperative PD-1Oncology letters · 2025Article
- Article
- Efficacy of nodal dissection for locoregional gastric neuroendocrine carcinoma: a multicenter retrospective observational study.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025Observational
- Current Status and Future Applications of Robotic Surgery in Upper Gastrointestinal Surgery: A Narrative Review.Cancers · 2025Review
- Beneath the Surface: The Emerging Role of Ultra-Processed Foods in Obesity-Related Cancer.Current oncology reports · 2025Review
- Safety and Efficacy of Conversion Therapy After Systemic Chemotherapy in Advanced Esophageal Cancer with Distant Metastases: A Multicenter Retrospective Observational Study.Annals of surgical oncology · 2025Observational
- Integrating serological and drainage fluid indicators: developing two predictive models for early detection of postoperative intra-abdominal infections in gastrointestinal tumor patients.Frontiers in oncology · 2025Article
- Higher rates of recurrence and worse quality of life in obese patients undergoing inguinal hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2024Article
- LightGBM is an Effective Predictive Model for Postoperative Complications in Gastric Cancer: A Study Integrating Radiomics with Ensemble Learning.Journal of imaging informatics in medicine · 2024Article
- Perioperative chemotherapy with nivolumab for HER2-negative locally advanced gastric cancer: a case series.Surgical case reports · 2024Article
- Article
- Risk factors of postoperative complications and their effect on survival after laparoscopic gastrectomy for gastric cancer.Annals of gastroenterological surgery · 2024Article
- Magnitude of in-hospital mortality and its associated factors among patients undergone laparotomy at tertiary public hospitals, West Oromia, Ethiopia, 2022.BMC surgery · 2024Article
- Article
- Risk factors for liver dysfunction and their clinical importance after gastric cancer surgery.Scientific reports · 2024Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe impact of postoperative complications on survival after radical surgery for esophageal, gastric, and colorectal cancers remains controversial. We conducted a systematic review of recent publications to examine the effect of postoperative complications on oncological outcome.
methodsA literature search of PubMed/MEDLINE was performed using the keywords "esophageal cancer," "gastric cancer," and "colorectal cancer," obtaining 27 reports published online up until the end of April 2016. Articles focusing on (i) postoperative morbidity and oncological outcome; and (ii) body mass index (BMI), postoperative morbidity, and oncological outcome, were selected. Univariate and multivariate analyses (Cox proportional hazards model) were performed.
resultsPatients with postoperative complications had significantly poorer long-term survival than those without complications. Complications were associated with impaired oncological outcomes. The hazard ratios for overall survival were 1.67 (95% confidence interval [CI], 1.31-2.12), 1.59 (95% CI, 1.13-2.24), and 1.55 (95% CI, 1.28-1.87) in esophageal, gastric, and colorectal cancers, respectively. High BMI was associated with postoperative morbidity rate but not with poor oncological outcome. Low BMI was significantly associated with inferior oncological outcome.
conclusionsComplications after radical surgery for esophageal, gastric, and colorectal cancers are associated with patient prognosis. Avoiding such complications might improve the outcomes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.