Evidence map›Paper›PMID 29862421›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2018

A new kit to detect Campylobacter species in stool specimens: the Orion GenRead Campylobacter®.

Alice Buissonnière, Lucie Bénéjat, Paul Charron, Emilie Bessède, Philippe Lehours, Guillaume Valdenaire, Olivier Richer, Francis Mégraud

Abstract read
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In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alice BuissonnièreFrench National Reference Centre for Campylobacters and Helicobacters, Bacteriology Laboratory, CHU Bordeaux, Bordeaux, France.
Lucie BénéjatFrench National Reference Centre for Campylobacters and Helicobacters, Bacteriology Laboratory, CHU Bordeaux, Bordeaux, France.
Paul CharronINSERM U1053 BaRITOn, University of Bordeaux, Bordeaux, France.
Emilie BessèdeFrench National Reference Centre for Campylobacters and Helicobacters, Bacteriology Laboratory, CHU Bordeaux, Bordeaux, France.
Philippe LehoursFrench National Reference Centre for Campylobacters and Helicobacters, Bacteriology Laboratory, CHU Bordeaux, Bordeaux, France.
Guillaume ValdenaireEmergency Department, CHU Bordeaux, Bordeaux, France.
Olivier RicherPediatric Emergency Department, CHU Bordeaux, Bordeaux, France.
Francis MégraudFrench National Reference Centre for Campylobacters and Helicobacters, Bacteriology Laboratory, CHU Bordeaux, Bordeaux, France. francis.megraud@chu-bordeaux.fr.ORCID http://orcid.org/0000-0002-2481-1612

Funding

Orionin Tutkimussäätiö Unrestricted grant
6 · The paper itself

Abstract

Campylobacter enteritis is the most frequent bacterial enteritis including in children. Its diagnosis suffers from the lack of sensitivity and delayed result of culture. Our aim was to test a new PCR-derived method for Campylobacter diagnosis in comparison to a composite reference. Patients presenting to the emergency ward of our hospital with enteric symptoms during the 2016 summer season were included. In addition to culture, an ELISA and an in-house real-time PCR were performed, as well as the new method (Orion GenRead Campylobacter) on all stool specimens. The composite reference used to consider a case positive for Campylobacter was either culture positive and in case of negative culture both the ELISA and real-time PCR positive. One hundred fifty patients were included, 64 being infants or children. There were 29 cases positive by the composite reference, with 19 of the 64 children (29.7%) and 10 of the 86 adults (11.6%). If performed alone, culture would have missed six cases. The Orion GenRead Campylobacter detected all the positives by the composite reference but also 12 cases negative by the composite reference (sensitivity 100%, specificity 90.1%). Given the characteristics of the new method, it can be used as a screening method for Campylobacter detection.

Indexed as

Bacterial Typing TechniquesReagent Kits, DiagnosticAdolescentAdultCampylobacterCampylobacter InfectionsChildChild, PreschoolEnzyme-Linked Immunosorbent AssayFecesFemaleHumansInfantMaleReal-Time Polymerase Chain ReactionSensitivity and SpecificityReagent Kits, DiagnosticCultureDiagnosisELISAEnteritisPCR

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.