Evidence map›Paper›PMID 29862318›Full record

ArticleJournal of epidemiological research2016

Results from implementing updated 2012 World Health Organization Guidance on early-warning indicators of HIV drug resistance in Zimbabwe.

More Mungati, Mutsa Mhangara, Janet Dzangare, Owen Mugurungi, Tsitsi Apollo, Elizabeth Gonese, Peter H Kilmarx, Christine C Chakanyuka-Musanhu, Gerald Shambira, Mufuta Tshimanga

Abstract read
In one paragraph

Article in Journal of epidemiological research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

More MungatiAIDS and TB Unit, Ministry of Health and Child Care, Harare, Zimbabwe.
Mutsa MhangaraAIDS and TB Unit, Ministry of Health and Child Care, Harare, Zimbabwe.
Janet DzangareAIDS and TB Unit, Ministry of Health and Child Care, Harare, Zimbabwe.
Owen MugurungiAIDS and TB Unit, Ministry of Health and Child Care, Harare, Zimbabwe.
Tsitsi ApolloAIDS and TB Unit, Ministry of Health and Child Care, Harare, Zimbabwe.
Elizabeth GoneseCenters for Disease Control and Prevention, Harare, Zimbabwe.
Peter H KilmarxCenters for Disease Control and Prevention, Harare, Zimbabwe.
Christine C Chakanyuka-MusanhuWorld Health Organization, Harare, Zimbabwe.
Gerald ShambiraDepartment of Community Medicine, University of Zimbabwe, Harare, Zimbabwe.
Mufuta TshimangaDepartment of Community Medicine, University of Zimbabwe, Harare, Zimbabwe.

Funding

CGH CDC HHS U2G GH000315World Health Organization 001
6 · The paper itself

Abstract

objectiveThis study evaluated the performance of sentinel sites in preventing the emergence of HIVDR using Early Warning Indicators (HIVDR EWI) survey.

methodsAdult and paediatric patient data on: On time pill pick up, Retention in care, Pharmacy stock-outs, and Dispensing practices was collected. Information from pharmacy registers was verified using facility-held cards. This was a cross-sectional analysis of retrospectively collected data from 72 sites providing both adult and paediatric ART as well as two providing adult ART only. All data were entered into and analysed using a WHO EWI data abstraction electronic tool.

resultsTwenty-one percent of sites providing adult and 4.2% of sites providing paediatric ART managed to meet the target for on time pill pick up. Retention in care indicator was met by 48.7% (95% CI: 36.9-60.6) of sites. ARV stock-outs occurred in 81.1% (95% CI: 70-89.3) adult sites and 63.9% (95% CI: 50-78.6) paediatric sites. ARVs were appropriately dispensed by 86.5% (95% CI: 75.6-93.3) of adult sites and 84.7% (95% CI: 74.3-92.1) of paediatric sites.

conclusionsMost sites had low performance in many indicators in this survey and failed to meet the recommended targets. Some policies such as the current buffer stock and storage outside Harare should be revised in order to improve site access to ARVs. The country should prioritize the provision of viral load testing services in all provinces. The electronic patient management system should be rolled out to all ART sites to improve patient tracking and monitoring by sites.

Indexed as

Early warning indicatorsRetentionStock-outsZimbabwe

Identifiers

PMID29862318
PMCPMC5983043

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.