ReviewJournal of ophthalmology2018
Nanophthalmos: A Review of the Clinical Spectrum and Genetics.
Review in Journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03748732 (Extensive Circumferential Partial Thickness Sclerectomy in Nanophthalmic Eyes), which is not on this map. Cited by 57 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Extensive Circumferential Partial Thickness Sclerectomy in Nanophthalmic Eyes
Who cites it
57 citing papers in PubMed, 3 syntheses or guidelines pooled it, 109 citations in OpenAlex.
- Multi-ancestry genome-wide association analyses of refractive error augment genetic discovery and polygenic prediction.Nature genetics · 2026Pooled it
- Risk factors for glaucoma in nanophthalmos - a systematic review and meta-analysis.BMC ophthalmology · 2025Pooled it
- Sclerectomies in nanophthalmos and idiopathic uveal effusion syndrome: a systematic review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Pooled it
- Asymmetric uveal effusion in bilateral nanophthalmos presenting as unilateral secondary angle closure: a rare case report.BMC ophthalmology · 2026Article
- Clinical course of a patient with PRSS56-associated nanophthalmos (isolated microphthalmia) and uveal effusion syndrome.Documenta ophthalmologica. Advances in ophthalmology · 2026Article
- Whole-exome sequencing identifies PRSS56 variants in Chinese patients with microphthalmia.BMC medical genomics · 2026Article
- Splicing variants in MYRF cause partial loss of function in the retinal pigment epithelium leading to nanophthalmos.JCI insight · 2026Article
- Medical management of post-phacoemulsification uveal effusion in nanophthalmos: A case report.American journal of ophthalmology case reports · 2026Article
- Case Report: Pars plana filtration in the treatment of nanophthalmos patients with secondary angle closure glaucoma.Frontiers in medicine · 2026Article
- Article
- FOXP4 Variants Are Associated With Plateau Iris and Angle Closure Glaucoma.Investigative ophthalmology & visual science · 2025Article
- Complications of cataract surgery in short adult eyes of < 20.5 mm axial length.Eye (London, England) · 2025Article
- Genetic Spectrum and Genotype-Phenotype Correlations in a Chinese Cohort With Nanophthalmos With Secondary Angle-Closure Glaucoma.Investigative ophthalmology & visual science · 2025Article
- A biometric survey of known and prospective murine models of posterior microphthalmia-nanophthalmia.Experimental eye research · 2025Article
- Posterior Microphthalmos With RPE Dysfunction Misdiagnosed as Macular Edema.Case reports in ophthalmological medicine · 2025Article
- Prevalence and clinical associations of relative anterior microphthalmos assessed with an optical biometer.Scientific reports · 2024Article
- Clinical and Genetic Characteristics of Patients with Peripheral Retinal Flecks in Koreans.Korean journal of ophthalmology : KJO · 2024Article
- The Role of the Ophthalmic Genetics Multidisciplinary Team in the Management of Inherited Retinal Degenerations-A Case-Based Review.Life (Basel, Switzerland) · 2024Article
- Phacoemulsification in Nanophthalmic Eye, a Way to Manage Glaucoma: Case Report.Case reports in ophthalmological medicine · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nanophthalmos is a clinical spectrum of disorders with a phenotypically small but structurally normal eye. These disorders present significant clinical challenges to ophthalmologists due to a high rate of secondary angle-closure glaucoma, spontaneous choroidal effusions, and perioperative complications with cataract and retinal surgeries. Nanophthalmos may present as a sporadic or familial disorder, with autosomal-dominant or recessive inheritance. To date, five genes (i.e.,
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.