ArticleChemical science2016
Cooperative duplex formation by synthetic H-bonding oligomers.
Article in Chemical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 43 citations in OpenAlex.
- Duplex-forming oligocarbamates with tunable nonbonding sites.Chemical science · 2024Article
- Synthetically encoded complementary oligomers.Nature reviews. Chemistry · 2023Review
- Sequence-selective duplex formation and template effect in recognition-encoded oligoanilines.Chemical science · 2023Article
- Recognition-Encoded Synthetic Information Molecules.Accounts of chemical research · 2023Article
- H-Bond Templated Oligomer Synthesis Using a Covalent Primer.Journal of the American Chemical Society · 2022Article
- Folding and duplex formation in mixed sequence recognition-encodedChemical science · 2021Article
- High-Fidelity Sequence-Selective Duplex Formation by Recognition-Encoded Melamine Oligomers.Journal of the American Chemical Society · 2021Article
- Applications of Discrete Synthetic Macromolecules in Life and Materials Science: Recent and Future Trends.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- Supramolecular catalysis by recognition-encoded oligomers: discovery of a synthetic imine polymerase.Chemical science · 2020Article
- Two-component assembly of recognition-encoded oligomers that form stable H-bonded duplexes.Chemical science · 2020Article
- Organogelating and narcissistic self-sorting behaviour of non-preorganized oligoamides.Chemical science · 2019Article
- Building blocks for recognition-encoded oligoesters that form H-bonded duplexes.Chemical science · 2019Article
- H-Bonded Duplexes based on a Phenylacetylene Backbone.Journal of the American Chemical Society · 2018Article
- Backbone conformation affects duplex initiation and duplex propagation in hybridisation of synthetic H-bonding oligomers.Organic & biomolecular chemistry · 2018Article
- Sequence-Selective Formation of Synthetic H-Bonded Duplexes.Journal of the American Chemical Society · 2017Article
- Supramolecular Copolymers: Structure and Composition Revealed by Theoretical Modeling.Journal of the American Chemical Society · 2017Article
- H-Bond Self-Assembly: Folding versus Duplex Formation.Journal of the American Chemical Society · 2017Article
- Supramolecular chemistry: Host in translation.Nature nanotechnology · 2017Article
- Template-directed synthesis of linear porphyrin oligomers: classical, Vernier and mutual Vernier.Chemical science · 2017Article
- Homochiral oligomers with highly flexible backbones form stable H-bonded duplexes.Chemical science · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A series of flexible oligomers equipped with phenol H-bond donors and phosphine oxide H-bond acceptors have been synthesised using reductive amination chemistry. H-bonding interactions between complementary oligomers leads to the formation of double-stranded complexes which were characterised using NMR titrations and thermal denaturation experiments. The stability of the duplex increases by one order of magnitude for every H-bonding group added to the chain. Similarly, the enthalpy change for duplex assembly and the melting temperature for duplex denaturation both increase with increasing chain length. These observations indicate that H-bond formation along the oligomers is cooperative despite the flexible backbone, and the effective molarity for intramolecular H-bond formation (14 mM) is sufficient to propagate the formation of longer duplexes using this approach. The product
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.