ArticleChemical science2015
Repurposing of oxazolone chemistry: gaining access to functionalized graphene nanosheets in a top-down approach from graphite.
Article in Chemical science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Engineered carbon electrode with graphene-cyclodextrin/ferrocenyl-carnosine nanoassembly for Mn(ii) detection.RSC advances · 2025Article
- Cancer-Related Intracellular Signalling Pathways Activated by DOXorubicin/Cyclodextrin-Graphene-Based Nanomaterials.Biomolecules · 2022Article
- Shedding Light on the Chemistry and the Properties of Münchnone Functionalized Graphene.Nanomaterials (Basel, Switzerland) · 2021Article
- Eco-Friendly 1,3-Dipolar Cycloaddition Reactions on Graphene Quantum Dots in Natural Deep Eutectic Solvent.Nanomaterials (Basel, Switzerland) · 2020Article
- Intracellular Fate and Impact on Gene Expression of Doxorubicin/Cyclodextrin-Graphene Nanomaterials at Sub-Toxic Concentration.International journal of molecular sciences · 2020Article
- Graphene-Based Strategies in Liquid Biopsy and in Viral Diseases Diagnosis.Nanomaterials (Basel, Switzerland) · 2020Review
- Recent Advances of Graphene-Based Strategies for Arsenic Remediation.Frontiers in chemistry · 2020Review
- SERS Sensing Properties of New Graphene/Gold Nanocomposite.Nanomaterials (Basel, Switzerland) · 2019Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Solvent-free 1,3-dipolar cycloaddition (1,3-DC) reactions between graphite flakes and mesoionic oxazolones were carried out by heating the resulting solid mixture at mild temperatures (70-120 °C). The direct functionalization and delamination of graphite flakes into few layers of graphene nanosheets was confirmed by micro-Raman and X-ray photoelectron spectroscopies, scanning transmission electron microscopy and thermogravimetric analysis. The 1,3-DC reactions of mesoionic dipoles have been investigated with density functional theory to model graphene, exploring three different pathways: center, corner and edge. These theoretical calculations highlighted that the 1,3-DC reaction can proceed both through a concerted mechanism competing with a stepwise one involving a zwitterionic intermediate. The irreversible decarboxylation inherent in the last step justifies the high degree of functionalization experimentally observed, representing the driving force of the process.
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Registered trials
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