ArticleChemical science2015
Oxatub[4]arene: a smart macrocyclic receptor with multiple interconvertible cavities.
Article in Chemical science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Acridane[4]Arenes: Scope of the Macro-Tetramerization, Derivatization Options, and Water-Soluble Derivatives.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- Novel macrocycles: from synthesis to supramolecular function.Beilstein journal of organic chemistry · 2026Article
- Beyond symmetric self-assembly and effective molarity: unlocking functional enzyme mimics with robust organic cages.Beilstein journal of organic chemistry · 2025Article
- Deep-Cavity Calix[4]naphth[4]arene Macrocycles: Synthesis, Conformational Features, and Solid-State Structures.Molecules (Basel, Switzerland) · 2024Article
- Controlled interconversion of macrocyclic atropisomers via defined intermediates.Nature communications · 2024Article
- Window[1]resorcin[3]arenes: A Novel Macrocycle Able to Self-Assemble to a Catalytically Active Hexameric Cage.JACS Au · 2024Article
- Hexahexyloxycalix[6]arene, a Conformationally Adaptive Host for the Complexation of Linear and Branched Alkylammonium Guests.Molecules (Basel, Switzerland) · 2023Article
- Molecular Recognition in an Aqueous Medium Using Water-Soluble Prismarene Hosts.Organic letters · 2022Article
- Xanthene[JACS Au · 2021Article
- Article
- An intramolecularly self-templated synthesis of macrocycles: self-filling effects on the formation of prismarenes.Chemical science · 2021Article
- "Texas-Sized" Molecular Boxes: From Chemistry to Applications.Molecules (Basel, Switzerland) · 2021Review
- Multiple Stimuli-Responsive Conformational Exchanges of Biphen[3]arene Macrocycle.Molecules (Basel, Switzerland) · 2020Article
- Calix[2]naphth[2]arene: A Class of Naphthalene-Phenol Hybrid Macrocyclic Hosts.Organic letters · 2020Article
- Prismarenes: A New Class of Macrocyclic Hosts Obtained by Templation in a Thermodynamically Controlled Synthesis.Journal of the American Chemical Society · 2020Article
- An Investigation into Rigidity-Activity Relationships in BisQAC Amphiphilic Antiseptics.ChemMedChem · 2019Article
- 2,3-Dibutoxynaphthalene-based tetralactam macrocycles for recognizing precious metal chloride complexes.Beilstein journal of organic chemistry · 2019Article
- Molecular recognition using tetralactam macrocycles with parallel aromatic sidewalls.Beilstein journal of organic chemistry · 2019Review
- Rational synthesis of benzimidazole[3]arenes by CuChemical science · 2018Article
- A conformationally adaptive macrocycle: conformational complexity and host-guest chemistry of zorb[4]arene.Beilstein journal of organic chemistry · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There are a large number of synthetic macrocyclic receptors in the literature. No particular one is suitable for all guests or purposes. For a broader guest binding scope or multiple purposes, a macrocycle with multiple interconvertible cavities will be advantageous. Here, we report a naphthalene-based macrocyclic receptor with an adaptable cavity, namely oxatub[4]arene. It has four representative conformations resulting from the flipping of naphthalene rings, each with a deep and well-defined cavity. Different guests select one host conformer or a combination of conformers. All the four conformers have been detected and characterized based on 2D NMR spectra and X-ray single crystal structures. Thermodynamically, these conformers constitute a reservoir, that responds to the structural changes of guests, and thus maximizes the association free energies. This smart macrocycle may provide a new platform for the construction of molecular machines and devices or stimuli-responsive materials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.