ArticleOncotarget2018
Predictors of surgical outcomes and survival in rectal cancer patients undergoing laparoscopic total mesorectal excision after neoadjuvant chemoradiation therapy: the interest of pelvimetry and restaging magnetic resonance imaging studies.
Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- The role of MRI pelvimetry in predicting technical difficulty and outcomes of open and minimally invasive total mesorectal excision: a systematic review.Techniques in coloproctology · 2020Pooled it
- Deep Learning-Based Prediction System for Surgical Difficulty in Rectal Cancer Patients Using MRI Pelvimetry.Yonsei medical journal · 2026Article
- Machine learning for predicting surgical difficulty of laparoscopic total mesorectal excision for rectal cancer: integrating MR-based pelvimetry and peritoneal reflection.Frontiers in medicine · 2026Article
- Machine learning combined with body composition predicts surgical difficulty in mid-low rectal cancer surgery.Annals of medicine · 2025Article
- A simple and effective evaluation method to determine the difficulty of total mesorectal excision for male patients with mid and lower rectal cancer.Techniques in coloproctology · 2025Article
- Influence of computed tomography-based pelvimetric parameters and surgical approaches on surgical difficulty in mid‑low rectal cancer.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2025Article
- Role of pelvimetry in predicting surgical outcomes and morbidity in rectal cancer surgery: A retrospective analysis.World journal of gastrointestinal surgery · 2025Article
- Deep learning-based pelvimetry in pelvic MRI volumes for pre-operative difficulty assessment of total mesorectal excision.Surgical endoscopy · 2025Article
- Article
- Interpretable machine learning model to predict surgical difficulty in laparoscopic resection for rectal cancer.Frontiers in oncology · 2024Review
- Pathologic complete response to TNT + camrelizumab for rectal cancer with surgical anus-preservation: case report and literature review.Frontiers in surgery · 2023Article
- An MRI-based pelvimetry nomogram for predicting surgical difficulty of transabdominal resection in patients with middle and low rectal cancer.Frontiers in oncology · 2022Article
- A nomogram predicting the difficulty of laparoscopic surgery for rectal cancer.Surgery today · 2021Article
- Commentary on "The role of MRI pelvimetry in predicting technical difficulty and outcomes of open and minimally invasive total mesorectal excision: a systematic review".Techniques in coloproctology · 2021Article
- Author's reply to commentary on "The role of MRI pelvimetry in predicting technical difficulty and outcomes of open and minimally invasive total mesorectal excision: a systematic review".Techniques in coloproctology · 2021Article
- Pelvimetric and Nutritional Factors Predicting Surgical Difficulty in Laparoscopic Resection for Rectal Cancer Following Preoperative Chemoradiotherapy.World journal of surgery · 2021Article
- MRI pelvimetry-based evaluation of surgical difficulty in laparoscopic total mesorectal excision after neoadjuvant chemoradiation for male rectal cancer.Surgery today · 2021Article
- Risk factors for suboptimal laparoscopic surgery in rectal cancer patients.Langenbeck's archives of surgery · 2021Article
- Prognostic Factors Affecting Short- and Long-Term Recurrence-Free Survival of Patients with Rectal Cancer using Cure Models: A Cohort Study.Iranian journal of medical sciences · 2020Article
- Non-operative management of rectal cancer.Seminars in colon & rectal surgery · 2019Article
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Authors and funding
14 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLocally advanced rectal cancer (LARC) requires a multimodal therapy tailored to the patient and tumor characteristics. Pretreatment magnetic resonance imaging (MRI) is necessary to stage the primary tumor, while restaging MRI, which is not systematically performed, may be of interest to identify poor responders to neoadjuvant chemoradiation therapy (NCRT), and redefine therapeutic approach. The
methodsPatients with mid or low LARC who were administered NCRT, who underwent laparoscopic total mesorectal excision, and for whom pretreatment and restaging MRIs were available, were included.
resultsMRIs of 170 patients (median age: 61 years) were reanalyzed by the same radiologist. Pelvimetry differed significantly between males and females, but no gender difference was noted in the clinical and tumor characteristics. Tumor volume and tumor height assessed on the restaging MRI were associated, respectively, with operative time and estimated blood loss. Conversion was predicted by tumor volume, interischial distance and pubic tubercle height. The quality of the surgical resection was found to be a predictor of overall and disease-free survival. The sensitivity and specificity of tumor regression grade 1 to identify a pathologic complete response were 76.9% and 89.3%, respectively.
conclusionsIn LARC management, pelvimetry and restaging MRI may be useful to predict surgical difficulties and surgical outcomes. However, the main independent predictor of patient survival appears to be the achievement of a successful surgical resection.
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